College of Medicine

Projects

Projects per year 2010 2013 2014 2015 2016 2017 2018 2019 2020 2021 2022 2026

• 2 Not started
• 245 Active
• 3059 Finished

Projects per year

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• Finished

  利用人工智慧虛擬篩選平台鑑定DNA聚合?theta之小分子抑制劑和評估其對於轉移型去勢抗性之攝護腺癌的治療效果(2/3)

  Lin, Y.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 遠紅外線改善線粒體功能對糖尿病小鼠胰島β細胞的保護作用及與SIRT1和PLZF相關機制的研究(3/3)

  Chen, C.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 藉由調控神經包網結構來改善早期社交孤立所誘發於模棱兩可的資訊下異常恐懼記憶連結的形成(1/3)

  Yang, C. H.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 探討KH-Type切割調控蛋白在腎細胞癌惡性進程中所扮演的角色(1/3)

  Chien, M.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 膠淋巴系統於混合型失智症之角色(1/2)

  Hu, C.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 骨質疏鬆及肌少症影像人工智能分析計畫

  Kuo, Y.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 探討YqiC蛋白特性以開發標靶抗生素並針對沙門氏菌抗生素抗藥性和侵襲性進行基因分析：以雙面向方法發展對抗沙門氏菌感染之新策略(2/3)

  Fang, S.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 發展以同步量測中樞與周邊系統功能性訊息為導向之年長跌倒患者步態復健評估(3/3)

  Chan, W. P.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 開發具有骨誘導性之溫感性水膠包埋凍乾型富含血小板纖維蛋白並結合人工代用骨複合型材料用於兔子臨界骨缺損之修補(1/3)

  Wong, C.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 英明格引發呼吸道過度敏感:肺C纖維的角色(3/3)

  Lin, Y.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 突觸支架蛋白Shank3調控神經發炎反應在急性缺血性腦中風之病理作用機制研究(2/2)

  Hsieh, C.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 芳香烴受體於眼科疾病之治療潛力機制探討-多環芳香烴受體缺陷改變視網膜色素上皮細胞的整合素訊息,促進視網膜發炎環境及損害視網膜功能之分子機轉(1/3)

  Li, C.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 調控半乳糖凝集素之免疫訊號重整作用對心房再塑與心律不整活性的病理機轉探討：一個新的治療心房顫動契機(3/3)

  Chen, Y.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 纖維細胞生長因子與其受體之訊息路徑在急性腎損傷中維持腎臟血管結構能力之角色研究

  Cheng, C.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 探討PINK1於肺癌代謝鏈的調控機轉並研發可以調控PINK1活性的藥物(3/3)

  Lin, E. P.

  8/1/20 → 7/31/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 探討芳香烴受體核轉位蛋白受器/丙酮酸去氫激酶1路徑在與化療相關的頭頸癌進展所扮演的角色(1/3)

  Chang, W.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 新穎癌幹細胞侵犯腳治療標靶之整合性蛋白質體、基因體、小分子與功 能篩選：聚焦細胞表面AMFR於侵犯性消化道癌症治療標的(1/3)

  Tsai, K. K.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 利用轉錄體學與蛋白質體學方法探討膀胱癌對鉑類藥物產生抗藥性之分子機轉研究並開發新的治療策略(第二年)

  Chen, C.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 標靶B型肝炎誘發之肝癌腫瘤生成與Sorafenib抗藥性之微環境：聚焦發炎激素與癌幹細胞特性之轉譯精準醫學研究與臨床意義-探討微環境發炎細胞激素與基因後生調節於B型肝炎病毒誘導之肝癌表現多能性幹細胞基因OCT4與Sorafenib抗藥性之調控機制與其臨床意義(3/3)

  Huang, Y.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 潛在臨終個案篩檢計分系統：應用死亡風險預測與機器學習於心臟衰竭與慢性腎臟衰竭患者之安寧療護需求評估

  Chang, S.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• Characterization of both carbapenem- and colistin-resistant Acinetobacter clinical isolates: mechanisms of antimicrobial resistance, virulence and fitness

  Huang, T.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• CHRNA7-p38MAPKs axis發炎基因網絡在巨噬細胞極化作用及對脂蛋白(a)引發冠狀動脈細胞痙攣的機制探討(2/3)

  Hung, M.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 闡明SPOCK1/PI3K/AKT訊息路徑在透明細胞腎細胞癌對舒尼替尼抗藥性的潛在機制

  Lee, W.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 肺纖維化之分子病理機制探討-ADAM17/preadipocyte factor-1在缺氧誘導CTGF表現及呼吸道纖維化角色探討(3/3)

  Chen, B.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 在動物模式下發展穿顱干擾波電刺激新技術應用於中風膀胱功能障礙復健治療(1/3)

  Peng, C.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 豬椎間盤纖維環的抗排斥優化應用於脊椎外科手術之纖維環修補

  Wu, L.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 建置公衛研究專用之衛星遙測影像環境資料自動化平台

  Chuang, T.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 慢性腎臟病之日夜週期失序(1/3)

  Wu, M.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• Etelcalcetide經由調控Nrf2和Klotho-AMPK路徑改善腎性骨病變的骨轉換、血管鈣化和腎臟纖維化

  Zheng, C.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 葡萄糖轉運接受器促進大腸癌轉移之臨床轉譯價值與機制探討:著重在腫瘤微環境研究及治療藥物之開發(3/3)

  Lin, C.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 建立探討膜蛋白折疊的研究平台(2/3)

  Chang, Y.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 建立傳染疾病的全球傳播風險預警架構：評估台灣與東亞區域的境外移入風險(2/2)

  Chuang, T.

  8/1/20 → 7/31/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 建立類神經網路模型以評估手術病患發生呼吸中止與低血氧的風險

  Chang, C.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 探討 CWH43 大腸直腸癌發展的角色及其調控機制

  Chang, Y.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 丙型干擾素抗性於上皮細胞間質轉化對免疫檢查點阻斷療法的影響

  Lin, C.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 以循環腫瘤細胞預測肝癌治療反應及其機制探討

  Chiou, J.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 高氧誘導的肺損傷由新生小鼠的肺和腸道微生物群相介導

  Chen, C.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 探討多環芳香烴受體缺陷重啟多能細胞特性之新穎路徑與應用

  Li, C.

  8/1/20 → 7/31/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 降解型細胞自噬藉由促進微小RNA miR-449a表現量抑制大腸直腸癌之進程進而發展治療大腸癌之新策略(1/2)

  Wu, S.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 結合奈米診斷治療、影像免疫基因圖譜與人工智慧於原發性與再復發膠質母細胞瘤之研究-開發新穎結構小分子抑制劑用來抑制血管生成和腫瘤微環境以治療原發性及復發性多型性神經膠質母細胞腦瘤患者(2/3)

  Huang, S.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 貧血孕婦經臨床治療之改善情形及營養攝取行為探討

  Bai, C.

  7/23/20 → 12/25/21

  Project: A - Government Institution › c - Ministry of Health and Welfare

• 柴油引擎微粒在胚胎肺部發育的纖維母細胞Yap/Taz調控衰老機轉之研究

  Chuang, H.

  7/1/20 → 2/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 探討溶酶體酸性磷酸酶二在轉移性大腸直腸癌幹細胞中扮演的角色

  Shen, Y.

  7/1/20 → 2/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• SEA調控肺部細胞發炎透過STAT 1 蛋白路徑之研究

  Cheng, P.

  7/1/20 → 2/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 探討纖連蛋白誘導牙齦上皮細胞間質轉化現象中α5β1整合素調節SHP2的角色

  Lin, C.

  7/1/20 → 2/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 新穎性苯並咪唑衍生物MFB之抗多型性神經膠質母細胞瘤之藥理活性評估與機轉探討

  Huang, S.

  7/1/20 → 2/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 價創計畫：微創手術AI輔助影像辨識系統-以婦科子宮動脈阻斷術為模型

  Chen, C.

  7/1/20 → 12/1/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• 探討慢性睡眠剝奪對口腔菌叢的影響，並闡明口腔菌叢引致認知功能失常的潛在機制

  Chang, H.

  7/1/20 → 2/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 智能垂足電刺激器之研發

  Peng, C.

  7/1/20 → 2/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 以3D列印技術研發創新吐氣訓練器之研究

  Peng, C.

  7/1/20 → 2/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology