College of Medicine

Projects

Projects per year 2010 2013 2014 2015 2016 2017 2018 2019 2020 2021 2022 2026

• 2 Not started
• 245 Active
• 3059 Finished

Projects per year

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• Finished

  遠紅外線改善線粒體功能對糖尿病小鼠胰島β細胞的保護作用及與SIRT1和PLZF相關機制的研究(3/3)

  Chen, C.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 血管內皮β-catenin活化於動靜脈廔管狹窄之角色

  Sue, Y.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 樺木酸可作為IRE1/XBP1/Herp路徑抑制劑以阻斷膠質母細胞瘤的增殖和存活(3/3)

  Lo, W.

  8/1/20 → 7/31/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 利用超高速藥物篩選平台鑑定活化轉錄因子3之小分子活化劑及其對慢性腎臟病之治療效果

  Chen, H.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 麻醉護理專業證照及進階制度之臨床能力架構與評量—客觀結構式臨床測驗(OSCE)與可信賴專業活動(EPA)等工具之建構與驗證研究(1/2)

  Chen, C.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 紫杉醇調控血小板活化、細胞凋亡和自我吞噬之分子機轉探討:體內及體外試驗(1/3)

  Lu, W.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 在慢性阻塞性氣喘中double cortin like kinase 1 (DCLK1)在thrombin誘導IL-8/CXCL8表現及氣道發炎的病理角色之研究(1/3)

  Chen, B.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 辛伐他汀抗腎細胞癌的作用，經由抑制代謝重編程從mTOR、PPAR到RhoA(2/3)

  Juan, S.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 探討生物時鐘所調控之新型態肝細胞分裂模式在肝臟生理功能及相關疾病中所扮演之角色(3/3)

  Chao, H.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 芳香烴受體於眼科疾病之治療潛力機制探討-探討芳香烴受體活化在青光眼病程的視網膜保護角色(1/3)

  Hsiao, G.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 乳癌細胞受體專一性RNA適體奈米質粒誘發第三型玻尿酸合成酵素的抗癌機制探討(1/3)

  Tu, S.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 在國際健康功能與身心障礙分類系統的架構下，探討蛋白質補充合併運動訓練對急慢性機構衰弱老人改善肌少症指數及身體活動功能之成效(2/3)

  Liou, T.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 肺纖維化之分子病理機制探討-探討Sema7A+調節型T細胞在肺部纖維化中第二型免疫反應的調控角色(3/3)

  Chen, C.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• A combined neuroimaging and immunological investigation of disconnectivity of neurotransmitter-related nuclei and its underlying mechanisms in bipolar disorder (1/2)

  Magioncalda , P.

  8/1/20 → 7/31/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 配對式神經調控模式應用於脊髓損傷者之前瞻神經復健技術開發-子計畫三：運用跨模態多項次神經影像技術探討神經調控模式對脊髓損傷者之神經可塑性與功能變化(2/3)

  Chan, W. P.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 在動物模式下發展穿顱干擾波電刺激新技術應用於中風膀胱功能障礙復健治療(1/3)

  Peng, C.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• anti-EGFR×anti-FAP雙辨識特異性抗體結合包覆抗癌藥物Irinotecan標靶微脂體治療胰臟癌之研究(3/3)

  Lin, S.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 轉錄因子Sp1在癌細胞抗藥性所扮演角色-花生四烯酸的代謝在Sp1對神經膠質瘤與肺癌抗藥性的陰陽作用中扮演的角色(2/3)

  Chang, W.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 調控半乳糖凝集素之免疫訊號重整作用對心房再塑與心律不整活性的病理機轉探討：一個新的治療心房顫動契機(3/3)

  Chen, Y.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 探討 ABCC3 調控基因/lncRNA 網絡，進而評估其抑制藥物 Fidaxomicin 作為增強 temozolomide 對腦瘤毒殺能力佐劑之可行性

  Chen, K.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 探討B型肝炎相關肝癌中HBx蛋白與其相關之表觀遺傳調控因子促進SENP1表現與癌幹細胞特性：HBx/SENP1之角色與臨床意義(3/3)

  Wu, Y.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 葡萄糖轉運接受器促進大腸癌轉移之臨床轉譯價值與機制探討:著重在腫瘤微環境研究及治療藥物之開發(3/3)

  Lin, C.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 長散在核元件-1甲基化及DNA甲基化標記5-甲基胞嘧啶與5-甲基-2'-脫氧胞?濃度及尿液總砷濃度與慢性腎臟病的相關性

  Hsueh, Y.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 藉由調控神經包網結構來改善早期社交孤立所誘發於模棱兩可的資訊下異常恐懼記憶連結的形成(1/3)

  Yang, C. H.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 發展以同步量測中樞與周邊系統功能性訊息為導向之年長跌倒患者步態復健評估(3/3)

  Chan, W. P.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 配對式神經調控模式應用於脊髓損傷者之前瞻神經復健技術開發-子計畫一: 在脊髓損傷動物模式下探討配對式神經調控之作用機制與療效(2/3)

  Peng, C.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 迷幻藥引致認知功能失常之表觀遺傳機制探討 - 評估白黎蘆醇於表觀遺傳修飾之治療成效

  Chang, H.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 血管性認知功能障礙之精準醫療-腦中風後認知障礙之病程軌跡及生物標記(3/3)

  Hu, C.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 以循環腫瘤細胞預測肝癌治療反應及其機制探討

  Chiou, J.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 針對肺癌轉移中樞神經系統發展特定適體(2/2)

  Lin, E. P.

  8/1/20 → 7/31/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 具機械強度、可降解及骨誘導能力之鎂基非晶質合金應用於高位脛骨截骨矯正術之骨填充楔開發(1/3)

  Chen, C.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 慢性腎臟病之日夜週期失序(1/3)

  Wu, M.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 認知功能缺損長者的平衡控制與動作策略：三維動作分析以及穿戴式雙重任務訓練裝置之開發及其於居家介入之成效(第二、三期)(1/2)

  Kuan, Y.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• ZFHX3 knockdown調控心房纖維化導致心房顫動病理性結構重塑之機轉探討

  Kao, Y.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 結合人工智慧與穿戴式裝置之不良姿勢矯正系統-II

  Chen, H.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 開發具有骨誘導性之溫感性水膠包埋凍乾型富含血小板纖維蛋白並結合人工代用骨複合型材料用於兔子臨界骨缺損之修補(1/3)

  Wong, C.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 英明格引發呼吸道過度敏感:肺C纖維的角色(3/3)

  Lin, Y.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 建立探討膜蛋白折疊的研究平台(2/3)

  Chang, Y.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 轉錄因子Sp1在癌細胞抗藥性所扮演角色-HDACs/Sp1-microRNA-106b~25軸在膠質母細胞瘤抗藥性扮演的角色(2/3)

  Chen, R.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 循環性miR-19b和miR-93做為早期診斷男性骨質疏鬆症之有效生物標誌的轉譯醫學研究(3/3)

  Chen, R.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 芳香烴受體於眼科疾病之治療潛力機制探討-多環芳香烴受體缺陷改變視網膜色素上皮細胞的整合素訊息,促進視網膜發炎環境及損害視網膜功能之分子機轉(1/3)

  Li, C.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• (教學實踐) 混合蟲卵(Mix-ova)玻片判讀補救教學成效評估計畫

  Liao, C.

  8/1/20 → 7/1/21

  Project: A - Government Institution › d - Ministry of Education

• 嗜伊紅性白血球陽離子蛋白衍生之細胞穿透胜肽對於調節過敏性發炎之研究- 促進STAT-6反義RNA之運送與表現(2/3)

  Lee, Y.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 寡糖經由調節發炎反應來保護急性腎損傷的機制研究

  Chen, T.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 豬椎間盤纖維環的抗排斥優化應用於脊椎外科手術之纖維環修補

  Wu, L.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 探討黃腐醇合併降血糖藥是否可調控粒線體失常並經由活化未摺疊蛋白反應所激發之AMPK-NRf2-ARE-Glo1路徑來逆轉雙羰基壓力導致之糖尿病腎脂毒性

  Chen, K.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 利用轉錄體學與蛋白質體學方法探討膀胱癌對鉑類藥物產生抗藥性之分子機轉研究並開發新的治療策略(第二年)

  Chen, C.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• Bicalutamide經Sirt3/p53引發腎膈細胞電子傳遞鏈複合體I缺陷而致細胞凋亡機制的探討-輔以Idebenone及MitoTempo提升氧化磷酸化系統及調節粒線體動態之治療策略評估

  Peng, C.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 突觸支架蛋白Shank3調控神經發炎反應在急性缺血性腦中風之病理作用機制研究(2/2)

  Hsieh, C.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 建立傳染疾病的全球傳播風險預警架構：評估台灣與東亞區域的境外移入風險(2/2)

  Chuang, T.

  8/1/20 → 7/31/21

  Project: A - Government Institution › b - Ministry of Science and Technology