Projects per year
- 750 - 800 out of 3,059 results
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Effects of Direct Renin Inhibitor on Visceral Adipose Tissue and Vascular Remodeling of Fructose-Fed Hypertensive Rats
8/1/14 → 7/31/15
Project: A - Government Institution › b - Ministry of Science and Technology
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Effects of Functional Electrical Stimulation Cycling and Central Neuromodulation on Motor Control in Stroke
8/1/14 → 7/31/15
Project: A - Government Institution › b - Ministry of Science and Technology
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The Role of CISD2 in the Female Reproductive System of Mammal
Chang, H.
8/1/14 → 7/31/15
Project: A - Government Institution › b - Ministry of Science and Technology
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Reflex Pelvic Floor Muscle Activities in Women with Urinary Incontinence (II)
8/1/14 → 7/31/15
Project: A - Government Institution › b - Ministry of Science and Technology
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Development of a Computerized Adaptive Testing of the Health Literacy in Stroke Rehabilitation
Hou, W.
8/1/14 → 7/31/15
Project: A - Government Institution › b - Ministry of Science and Technology
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An Investigation of the Effects of Tea Component on the Inhibition of Leukocyte Nicotinic Acetylcholine Receptor Expression on Breast Cancer Patients
8/1/14 → 7/31/15
Project: A - Government Institution › b - Ministry of Science and Technology
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To Study the Correlation between Serum Markers of Oxidative Stress, Inflammation, and Endocrine-Disrupting Chemicals (Edcs) and Their Impact on the Menstrual Cycle and Reproductive Hormone in Taiwanese Women.
Hsu, M.
8/1/14 → 7/31/15
Project: A - Government Institution › b - Ministry of Science and Technology
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Role of Oxidative Stress-triggered Redox Adaptation Mechanism and Genetically Endowed Expression Profile of Antioxidant Enzymes in the modulation of Intrinsic and Acquired Chemoand Radio-resistance of Human Hepatocellular Carcinoma Cells
8/1/14 → 7/31/15
Project: A - Government Institution › b - Ministry of Science and Technology
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Investigation of Glioblastoma Cell-Secreted microRNA Signatures and Their Functional Effects on Tumor Angiogenesis
8/1/14 → 7/31/15
Project: A - Government Institution › b - Ministry of Science and Technology
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Molecular and Cellular Mechanism of Adipocyte Modulatory Effects on Pulmonary Vein and Atrium
8/1/14 → 7/31/15
Project: A - Government Institution › b - Ministry of Science and Technology
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Establish the Research Platform for Studying Triple-Negative Breast Tumor Microenvironment Regulation: the Hyaluronan Synthase-3 Mediated Antitumor Effects as an Example.
Ho, Y. & Wu, C.
8/1/14 → 7/31/15
Project: A - Government Institution › b - Ministry of Science and Technology
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The Imapct of Oxidative Stress on the Pathogenesis of COPD---An Ivestigation into Its Relationship with Abnormal Inflammation, Dna Instability, Epigenetics and Cell Metabolism
8/1/14 → 7/31/15
Project: A - Government Institution › b - Ministry of Science and Technology
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腫瘤相關巨噬細胞在誘發產生表皮生長因子受器酪胺酸酉每抑制劑的抗藥性的角色
8/1/14 → 7/31/15
Project: A - Government Institution › b - Ministry of Science and Technology
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乳癌是目前世界上女性癌症病患中為數最多的癌症之ㄧ。腺病毒蛋白type 5 E1A (E1A)和許多抗腫瘤作用有關，曾於多種癌症如乳癌、卵巢癌及頭頸癌之病患進行臨床基因治療試驗。許多的研究指出E1A具有多項抗腫瘤的功能，包括抑制腫瘤的發生、增加腫瘤細胞對於化療藥物的感受性以及減少腫瘤轉移的現象。腫瘤的轉移對於癌症患者的死亡率有極大的影響當然也包括了乳癌的患者。E1A於抑制腫瘤發展的過程中具有多重生物學上的意義，這也促使我們想要釐清E1A抑制癌症的機制。因此，我們對於了解E1A抑制癌症轉移相關的分子機制感到有興趣，並期望藉以作為未來改進乳癌病人臨床試驗的基石。我們初步的實驗結果顯示，E1A可以有效的抑制Glucose-regulated protein 78 (GRP78)這種已被廣泛報導和腫瘤惡化及轉移相關的蛋白的表現。 提出此研究計劃之目的在於詳細探討E1A所造成的抑制癌轉移作用中，GRP78所扮演的生物功能及其調控的機轉。為了達到此目的，我們將著重於E1A如何調控GRP78表現並進而展現對乳癌轉移的抑制作用。以下為此項研究計畫的四大主要目標： 目標一：探討GRP78在E1A所抑制之癌細胞移行及侵入作用中所扮演的角色 目標二：研究E1A抑制GRP78表現之分子機轉 目標三：於動物模式中驗證GRP78的表現對於E1A抗腫瘤作用的影響 目標四：探討GRP78及其相關分子的表現在乳癌病人的臨床重要性 完成以上的主要目標能夠幫助我們對於E1A之抗腫瘤轉移作用建立更加詳細的分子訊息傳遞機制。另外，藉由此研究計畫的新發現也許可以對未來發展癌症治療上提供更多具有潛力的標的物。
8/1/14 → 7/31/15
Project: A - Government Institution › b - Ministry of Science and Technology
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Study the Therapeutic Effects and Novel Molecular Mechanisms of Resveratrol in Human Osteosarcoma---The Treatment of Metastatic Cancer
8/1/14 → 7/31/15
Project: A - Government Institution › b - Ministry of Science and Technology
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Electrophysiological and Molecular Insights into the Cardiac Regulations of ZFHX3 Gene---Implication in the Pathophysiology of Atrial Fibrillation
8/1/14 → 7/31/15
Project: A - Government Institution › b - Ministry of Science and Technology
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Effects of Uteroplacental Insufficiency and Hyperoxia on Lung Development and Epigenetic Alterations in the Rat Offspring
8/1/14 → 7/31/15
Project: A - Government Institution › b - Ministry of Science and Technology
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Functional Role of Growth Factor-Induced Metabolic Enzymes Expression in Cancer Cell Anti-Oxidation and Drug Resistance
8/1/14 → 7/31/15
Project: A - Government Institution › b - Ministry of Science and Technology
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The Relationship and Predictors of Electrocardiography, Inflammatory Markers, Clinical Features in Older Bipolar and Schizophrenia Patients Concurrent with Coronary Heart and Cerebro-Vascular Diseases
8/1/14 → 7/31/15
Project: A - Government Institution › b - Ministry of Science and Technology
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Molecular Epidemiological Study of Renal Cell Carcinoma---Arsenic Methylation Capability, 8-OHdG and Polymorphism of IRS and RAAS Exploration
Hsueh, Y.
8/1/14 → 7/31/15
Project: A - Government Institution › b - Ministry of Science and Technology
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Study of Nano-Size Memberane Tube for Tendon to Bone in Anterior Cruciate Ligament Reconstruction
8/1/14 → 7/31/15
Project: A - Government Institution › b - Ministry of Science and Technology
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Biomarkers Associated with Toll-Like Receptors and Neuroimage Study in Ischemic Stroke Patients (II)
8/1/14 → 7/31/15
Project: A - Government Institution › b - Ministry of Science and Technology
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Therapeutic Strategies for Traumatic Brain Injury with Novelly Desinged Drugs (III)
8/1/14 → 7/31/15
Project: A - Government Institution › b - Ministry of Science and Technology
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肝醣合成酉每激酉每3於登革病毒感染單核吞噬細胞的潛在角色(2/3)
8/1/14 → 7/31/15
Project: A - Government Institution › b - Ministry of Science and Technology
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肺纖維化之轉譯研究－組蛋白去乙醯酉每2的SUMO化修飾貢獻於慢性阻塞性氣喘的結締組織生長因子表現與肺部纖維化反應(2/3)
8/1/14 → 7/31/15
Project: A - Government Institution › b - Ministry of Science and Technology
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Role of Organic Anion Transporter in Renal Tubular Injury---A Gateway to Hurt
8/1/14 → 7/31/15
Project: A - Government Institution › b - Ministry of Science and Technology
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Translational Studies of Mycobacterium tuberculosis-Induced Lung and Pleural Fibrosis
8/1/14 → 10/31/15
Project: A - Government Institution › b - Ministry of Science and Technology
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Translational Investigation for Tea Attenuate Smoking-Induced Disease---Breast Cancer and Atherosclerosis as a Mechanistic Study
Ho, Y.
8/1/14 → 7/31/15
Project: A - Government Institution › b - Ministry of Science and Technology
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Dissected the Role of Glucosed-Regulated Portein 78 in the Progression, Metastasis and Therapy of Colorectal Cancer
8/1/14 → 7/31/15
Project: A - Government Institution › b - Ministry of Science and Technology
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Effects and Mechanisms of Pitx2c Modulation for Atrial Electrophysiological and Structural Remodelings in Heart Failure
8/1/14 → 7/31/15
Project: A - Government Institution › b - Ministry of Science and Technology
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The Study of Therapeutic Effects for Stroke with Phenserine, an Amyloid Precursor Protein Inhibitor, in Rodent Focal Cerebral Ischemia Model(2/3)
Chang, C. & Chiang, Y.
8/1/14 → 7/31/15
Project: A - Government Institution › a - National Health Research Institutes
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Serum Free Cultivation of Multi-Layered Oral Mucosa Epithelial Cell Sheet for Autologous Corneal Epithelium Repairing and Its Animal Model
8/1/14 → 7/31/15
Project: A - Government Institution › b - Ministry of Science and Technology
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Unraveling the Impact of Deletion of Androgen Receptor on Brain Trauma
Yang, L.
8/1/14 → 7/31/15
Project: A - Government Institution › b - Ministry of Science and Technology
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The Role of CD24 in TNF-Alpha-Inhibited Erythroid Differentiation
8/1/14 → 7/31/15
Project: A - Government Institution › b - Ministry of Science and Technology
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Optimization of Human Meniscus Imaging and Its Clinical Application for Osteoarthritis (II)
Tsai, P.
8/1/14 → 10/31/15
Project: A - Government Institution › b - Ministry of Science and Technology
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The Impact of Functional Connectivity MR Imaging Study in the Correlation of the Surgical Outcome Validations and Neuroplasticity of Lumbar Spinal Stenosis with Neurogenic Intermittent Claudication
8/1/14 → 7/31/16
Project: A - Government Institution › b - Ministry of Science and Technology
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Evaluation of Clinical Feasibility of Quantitative MR Perfusion Imaging and Its Calibration
8/1/14 → 7/31/15
Project: A - Government Institution › b - Ministry of Science and Technology
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A Study on Trans-Neuronal Striato-Nigral Degeneration-Induced Movement Disorders after Stroke---Evaluation with Grey Matter Suppression Ir and Diffusion Tensor Imaging (III)
8/1/14 → 10/31/15
Project: A - Government Institution › b - Ministry of Science and Technology
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The Effects of the APOE4 Allele on Cerebral Structural and Functional Connectivity---A Diffusion Tensor Imaging and Resting-State MRI Study
Chen, C.
8/1/14 → 7/31/15
Project: A - Government Institution › b - Ministry of Science and Technology
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The Novel Roles of Aldose Reductase (AR) in Collagen GPVI- and Thrombin PAR4-Mediated Platelet Activation and Apoptosis---Regulatory Machinery of Arf-AR Signaling in Anucleate Cells
8/1/14 → 7/31/15
Project: A - Government Institution › b - Ministry of Science and Technology
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The Effect of Physical Exercise Program on Pro-Inflammatory and Anti-Inflammatory Cytokines in Patients with Chronic Obstructive Pulmonary Disease
8/1/14 → 7/31/15
Project: A - Government Institution › b - Ministry of Science and Technology
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Can Sesamin Alone or Cotheapy with Anti-DM Medicines Alleviate the Abnormal Intermediate Metabolites of Glucose and Fatty Acids, the Oxygen Consumption and Renal Fibrotic Progression?
8/1/14 → 7/31/15
Project: A - Government Institution › b - Ministry of Science and Technology
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Effects of Different Sources of n-3 Fatty Acids on Bone Loss, Body Fat and Inflammatory Markers in Osteoporotic Condition with Diabetes
8/1/14 → 7/31/15
Project: A - Government Institution › b - Ministry of Science and Technology
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Role of ER Stress in Evodiamine-Induced Apoptosis and G2/M Arrest of Human Colorectal Carcinoma Cells
Chen, Y.
8/1/14 → 7/31/15
Project: A - Government Institution › b - Ministry of Science and Technology
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The Effects of Adipose-Derived Stem Cells on Denervated Rat Skeletal Muscle Atrophy
8/1/14 → 7/31/15
Project: A - Government Institution › b - Ministry of Science and Technology
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The Effect of Endothelin-1 on Myofibroblast Transformation of Pleural Mesothelial Cells and Its Implications for Pleural and Pulmonary Fibrosis
8/1/14 → 7/31/15
Project: A - Government Institution › b - Ministry of Science and Technology
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The Effect of Muscle Strength Training on Body Composition and Sarcopenic Obesity among the Female Overweight Elderly
8/1/14 → 7/31/15
Project: A - Government Institution › b - Ministry of Science and Technology
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Evaluate the Radio-Biological Roles of miR-17-5P in Oral Cancer Cell Line OC3
Wu, S.
8/1/14 → 7/31/15
Project: A - Government Institution › b - Ministry of Science and Technology
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探討不同選擇作用之組織蛋白去乙醯?調節成分抑制神經發炎之機制及其對腦內出血與腦炎之治療特性評估(2/3)
8/1/14 → 7/31/15
Project: A - Government Institution › b - Ministry of Science and Technology