Projects per year
- 2,500 - 2,550 out of 3,267 results
Search results
-
To Predict the Recurrence of Major Depressive Disorder Within an Integrated Bio-Psycho-Social Framework---A Follow-up Study
8/1/14 → 7/31/15
Project: A - Government Institution › b - National Science and Technology Council
-
To Investigate the Role of SPNS2 in Determining Individual Susceptibility to Hypoxic Challenge
8/1/14 → 7/31/15
Project: A - Government Institution › b - National Science and Technology Council
-
The Effect of Muscle Strength Training on Body Composition and Sarcopenic Obesity among the Female Overweight Elderly
8/1/14 → 7/31/15
Project: A - Government Institution › b - National Science and Technology Council
-
Molecular Mechanisms of a Novel Aliphatic Hydroxamate, WMJ-S-001, in Suppressing Colorectal Cancer Progression---The Causal Role of AMPK-p53 Modification-miRNAs Cascade
8/1/14 → 7/31/15
Project: A - Government Institution › b - National Science and Technology Council
-
探討精神分裂症治療藥物Chlorpromazine促進大腸直腸癌細胞凋亡及SIRT1-P53的調控機制
3/1/14 → 7/31/15
Project: C - Project of Alliance › o - Chi Mei Medical Center
-
Electrophysiological and Molecular Insights into the Cardiac Regulations of ZFHX3 Gene---Implication in the Pathophysiology of Atrial Fibrillation
8/1/14 → 7/31/15
Project: A - Government Institution › b - National Science and Technology Council
-
Biomarkers Associated with Toll-Like Receptors and Neuroimage Study in Ischemic Stroke Patients (II)
8/1/14 → 7/31/15
Project: A - Government Institution › b - National Science and Technology Council
-
Kidney Injury and Heat Shock Protein Modulate the Atrial Electrophysiological Characterisitcs
8/1/14 → 7/31/15
Project: A - Government Institution › b - National Science and Technology Council
-
Cellular and Molecular Mechanisms of Nicotine and Nitrosamines Promote Tumorigenic Behaviors in Renal Cell Carcinoma (II)
8/1/14 → 7/31/15
Project: A - Government Institution › b - National Science and Technology Council
-
The Imapct of Oxidative Stress on the Pathogenesis of COPD---An Ivestigation into Its Relationship with Abnormal Inflammation, Dna Instability, Epigenetics and Cell Metabolism
8/1/14 → 7/31/15
Project: A - Government Institution › b - National Science and Technology Council
-
肝醣合成酉每激酉每3於登革病毒感染單核吞噬細胞的潛在角色(2/3)
8/1/14 → 7/31/15
Project: A - Government Institution › b - National Science and Technology Council
-
Study of Postoperative Adverse Outcomes of Surgical Patients Using Taiwan National Health Insurance Database
8/1/14 → 7/31/15
Project: A - Government Institution › b - National Science and Technology Council
-
Serum Free Cultivation of Multi-Layered Oral Mucosa Epithelial Cell Sheet for Autologous Corneal Epithelium Repairing and Its Animal Model
8/1/14 → 7/31/15
Project: A - Government Institution › b - National Science and Technology Council
-
Application of Scaffold in Ovarian Transplantation for Female Fertility Preservation---An in vivo Transgenic Mouse Model (I)
8/1/14 → 7/31/15
Project: A - Government Institution › b - National Science and Technology Council
-
Can Sesamin Alone or Cotheapy with Anti-DM Medicines Alleviate the Abnormal Intermediate Metabolites of Glucose and Fatty Acids, the Oxygen Consumption and Renal Fibrotic Progression?
8/1/14 → 7/31/15
Project: A - Government Institution › b - National Science and Technology Council
-
粒狀空氣污染物所產生的氧化壓力對慢性阻塞性肺疾病患者的泛素-蛋白酉每平衡系統之影響:探討氧化壓力，異常發炎以及蛋白質氧化之關係
8/1/14 → 7/31/15
Project: A - Government Institution › b - National Science and Technology Council
-
Effects and Mechanisms of Pitx2c Modulation for Atrial Electrophysiological and Structural Remodelings in Heart Failure
8/1/14 → 7/31/15
Project: A - Government Institution › b - National Science and Technology Council
-
Wnt/Tenascin Regulates Neurotrophin-Induced Neuronal Transdifferentiation of Human Bone Marrow-Derived Mesenchymal Stem Cells in 2d and 3d Cultures
Lai, W.
8/1/14 → 7/31/15
Project: A - Government Institution › b - National Science and Technology Council
-
The Role of CISD2 in the Female Reproductive System of Mammal
Chang, H.
8/1/14 → 7/31/15
Project: A - Government Institution › b - National Science and Technology Council
-
Effects of Functional Electrical Stimulation Cycling and Central Neuromodulation on Motor Control in Stroke
8/1/14 → 7/31/15
Project: A - Government Institution › b - National Science and Technology Council
-
CXCL5/CXCR2/JNK Axis Is the Shared Pathway of Neuroinflammation and Microvascular Damage That Contributes to White Matter Injury in the Immature Brain
Huang, C.
8/1/14 → 7/31/15
Project: A - Government Institution › b - National Science and Technology Council
-
Efficacy Studies of Tn-Directed Therapeutic Antibody and Immunotoxin in Syngeneic Mouse Tumor Models
Hwang, J.
8/1/14 → 7/31/15
Project: A - Government Institution › b - National Science and Technology Council
-
Relationships of One-Carbon Cycle Pathways with Psychopathology and Metabolic Abnormalities in Patients with Schizophrenia and Potential Intervention Strategy with 5-Methyltetrahydrofolate and Vitamin B12
8/1/14 → 7/31/15
Project: A - Government Institution › b - National Science and Technology Council
-
Pragmatic Challenges to Contemporary Vi Sions on Professionalism in Taiwan and Western Countries：Proposing and Evaluating a Situational and Relational Learning Paradigm Based upon Community Mental Health
Tsai, D.
8/1/14 → 7/31/15
Project: A - Government Institution › b - National Science and Technology Council
-
The Neurotrophic/Neuroprotective Role of GIP in Cellular and Rodent Models of Mild Traumatic Brain Injury (III)
8/1/14 → 7/31/15
Project: A - Government Institution › b - National Science and Technology Council
-
An Investigation of the Effects of Tea Component on the Inhibition of Leukocyte Nicotinic Acetylcholine Receptor Expression on Breast Cancer Patients
8/1/14 → 7/31/15
Project: A - Government Institution › b - National Science and Technology Council
-
組蛋白去甲基酉每JARID1B基因在肺腺癌之腫瘤形成與影響腫瘤生物行為機轉之探討(1/2)
8/1/14 → 7/31/15
Project: A - Government Institution › b - National Science and Technology Council
-
The Effects of Metabolic Abnormalities on Cognitive Function in Schizophrenic Patients
8/1/14 → 7/31/15
Project: A - Government Institution › b - National Science and Technology Council
-
氧化還原作用調控蛋白質去磷酸酉每羰基化和去羰基化反應對動脈血管內膜增生之影響(1/2)
8/1/14 → 7/31/15
Project: A - Government Institution › b - National Science and Technology Council
-
Investigation of Glioblastoma Cell-Secreted microRNA Signatures and Their Functional Effects on Tumor Angiogenesis
8/1/14 → 7/31/15
Project: A - Government Institution › b - National Science and Technology Council
-
Highly Reliable Surface-Enhanced Raman Scattering Sensors
8/1/14 → 7/31/15
Project: A - Government Institution › b - National Science and Technology Council
-
The Effects of the APOE4 Allele on Cerebral Structural and Functional Connectivity---A Diffusion Tensor Imaging and Resting-State MRI Study
Chen, C.
8/1/14 → 7/31/15
Project: A - Government Institution › b - National Science and Technology Council
-
Unraveling the Impact of Deletion of Androgen Receptor on Brain Trauma
Yang, L.
8/1/14 → 7/31/15
Project: A - Government Institution › b - National Science and Technology Council
-
Evaluation of Clinical Feasibility of Quantitative MR Perfusion Imaging and Its Calibration
8/1/14 → 7/31/15
Project: A - Government Institution › b - National Science and Technology Council
-
The Role of ADAM 17 in Hypoxia-Induced CTGF Expression and Pulmonary Fibrosis (II)
8/1/14 → 7/31/15
Project: A - Government Institution › b - National Science and Technology Council
-
探討不同選擇作用之組織蛋白去乙醯?調節成分抑制神經發炎之機制及其對腦內出血與腦炎之治療特性評估(2/3)
8/1/14 → 7/31/15
Project: A - Government Institution › b - National Science and Technology Council
-
Dissected the Role of Alpha-7 Nicotinic Receptor in the Prognosis and Clinical Therapy on Gastric Cancers
8/1/14 → 7/31/15
Project: A - Government Institution › b - National Science and Technology Council
-
Functional Investigation of Heat Shock Protein in Esophageal Squamous Cell Cancer with Implications in Prognostic Prediction and Therapeutic Targeting
Tzao, C.
8/1/14 → 7/31/15
Project: A - Government Institution › b - National Science and Technology Council
-
Anti-Aging Effect with the Associated Mechanism by PRP (Platelet-Rich Plasma) in Cartilage---A Fibronectin Fragment Model
8/1/14 → 7/31/15
Project: A - Government Institution › b - National Science and Technology Council
-
The Influence of Porphyromonas gingivalis Groel in Vascular Cells
8/1/14 → 7/31/15
Project: A - Government Institution › b - National Science and Technology Council
-
Molecular and Cellular Mechanism of Adipocyte Modulatory Effects on Pulmonary Vein and Atrium
8/1/14 → 7/31/15
Project: A - Government Institution › b - National Science and Technology Council
-
Study the Function and Regulation of miRNAs in Pancreatic Cancer Progression (I)
Huang, M.
8/1/14 → 7/31/15
Project: A - Government Institution › b - National Science and Technology Council
-
榖胱甘月太硫轉移酉每參與乳癌致癌之分子機制探討(3/3)
Wu, C.
8/1/14 → 7/31/15
Project: A - Government Institution › b - National Science and Technology Council
-
The Novel Roles of Aldose Reductase (AR) in Collagen GPVI- and Thrombin PAR4-Mediated Platelet Activation and Apoptosis---Regulatory Machinery of Arf-AR Signaling in Anucleate Cells
8/1/14 → 7/31/15
Project: A - Government Institution › b - National Science and Technology Council
-
乳癌是目前世界上女性癌症病患中為數最多的癌症之ㄧ。腺病毒蛋白type 5 E1A (E1A)和許多抗腫瘤作用有關，曾於多種癌症如乳癌、卵巢癌及頭頸癌之病患進行臨床基因治療試驗。許多的研究指出E1A具有多項抗腫瘤的功能，包括抑制腫瘤的發生、增加腫瘤細胞對於化療藥物的感受性以及減少腫瘤轉移的現象。腫瘤的轉移對於癌症患者的死亡率有極大的影響當然也包括了乳癌的患者。E1A於抑制腫瘤發展的過程中具有多重生物學上的意義，這也促使我們想要釐清E1A抑制癌症的機制。因此，我們對於了解E1A抑制癌症轉移相關的分子機制感到有興趣，並期望藉以作為未來改進乳癌病人臨床試驗的基石。我們初步的實驗結果顯示，E1A可以有效的抑制Glucose-regulated protein 78 (GRP78)這種已被廣泛報導和腫瘤惡化及轉移相關的蛋白的表現。 提出此研究計劃之目的在於詳細探討E1A所造成的抑制癌轉移作用中，GRP78所扮演的生物功能及其調控的機轉。為了達到此目的，我們將著重於E1A如何調控GRP78表現並進而展現對乳癌轉移的抑制作用。以下為此項研究計畫的四大主要目標： 目標一：探討GRP78在E1A所抑制之癌細胞移行及侵入作用中所扮演的角色 目標二：研究E1A抑制GRP78表現之分子機轉 目標三：於動物模式中驗證GRP78的表現對於E1A抗腫瘤作用的影響 目標四：探討GRP78及其相關分子的表現在乳癌病人的臨床重要性 完成以上的主要目標能夠幫助我們對於E1A之抗腫瘤轉移作用建立更加詳細的分子訊息傳遞機制。另外，藉由此研究計畫的新發現也許可以對未來發展癌症治療上提供更多具有潛力的標的物。
8/1/14 → 7/31/15
Project: A - Government Institution › b - National Science and Technology Council
-
Therapeutic Strategies for Traumatic Brain Injury with Novelly Desinged Drugs (III)
8/1/14 → 7/31/15
Project: A - Government Institution › b - National Science and Technology Council
-
Explore the Molecular Mechanisms and Application of microRNA-16 in In Acute Kidney Injury
8/1/14 → 7/31/15
Project: A - Government Institution › b - National Science and Technology Council
-
Effects of Ultrafine Particles on Cardiopulmonary System: a Population-Based Approach
8/1/14 → 7/31/15
Project: A - Government Institution › b - National Science and Technology Council
-
Investigation of the Transcriptional and Epigenetic Mechanisms for the Nm23-H1 Expression---An Nm23-H1-Promoter Screening Platform for Novel Metastasis-Suppressing Anticancer Drugs
Wang, L.
8/1/14 → 7/31/15
Project: A - Government Institution › b - National Science and Technology Council
-
Determined the Role and the Mechanims of GRP94 in Mediating the Progression and Therapeutic Responses of HCC
Huang, M.
8/1/14 → 7/31/15
Project: A - Government Institution › b - National Science and Technology Council