College of Medicine

Projects

Projects per year 2010 2013 2014 2015 2016 2017 2018 2019 2020 2021 2022 2026

• 2 Not started
• 245 Active
• 3059 Finished

Projects per year

Search results

• 探討Dicer在胰臟癌細胞對gemcitabine感受性的影響及其調控機制(1/3)

  Su, Y.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

• The Investigation of Anti-Neuroinflammatory Mechanisms of Differential Histone Deacetylase Regulators and Their Therapeutic Profiles in Experimental Intracerebral Haemorrahge and Encephalitis

  Hsiao, G.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Encephalitis 100%
  • Monocytes 77%
  • Acetylation 73%
  • Microglia 71%
  • Psychological Inhibition 57%

• Identification of Roles of microRNAs in Drug Resistance Development of Chronic Myeloid Leukemia

  Shih, C. & Liu, H.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • MicroRNAs 100%
  • Leukemia, Myelogenous, Chronic, BCR-ABL Positive 87%
  • Drug Resistance 40%
  • Imatinib Mesylate 29%
  • ran GTP-Binding Protein 29%

• Short-Chain Fatty Acids Act as Anti-Allergic Regulators on Immune Effector Cells and Exert Immune-Modulatory Effects on Ovalbumin-Induced Allergic Diseases in Mice

  Lee, Y. & Hsiao, G.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Volatile Fatty Acids 100%
  • Phenylbutyrates 27%
  • Mast Cells 25%
  • Immunoglobulin E 19%
  • Asthma 16%

• The Impact of Functional Connectivity MR Imaging Study in the Correlation of the Surgical Outcome Validations and Neuroplasticity of Lumbar Spinal Stenosis with Neurogenic Intermittent Claudication

  Huang, T.

  8/1/14 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Intermittent Claudication 100%
  • Spinal Stenosis 39%
  • Brain 26%
  • Neuronal Plasticity 22%
  • Chronic Pain 14%

• TMU103-AE1-B37

  Wu, J.

  8/1/15 → 7/31/16

  Project: B - Project of TMU › i - Other (Funded by TMU)

• Whole Organ Decellularizationtrachea Scaffold Tissue Engineering for Whole Segment Tracheal Transplantation/Replacement

  Hung, S., Lee, F. & Tseng, H.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • trachea (vertebrates) 100%
  • cartilage 77%
  • sonication 70%
  • tissues 27%
  • skeleton 25%

• Redox Modulation of Protein Phosphatases by Protein Carbonylation/De-Carbonylation Process in Arterial Neointimal Hyperplasia

  Hsieh, C.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Phosphoprotein Phosphatases 100%
  • Protein Carbonylation 84%
  • Oxidation-Reduction 47%
  • Protein Tyrosine Phosphatases 35%
  • Hyperplasia 31%

• The Comparison of Complications and Mortality after Surgery between General Anesthesia and Regional Anesthesia in the Elderly

  Liao, C., Cherng, Y. & Chen, T.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Conduction Anesthesia 100%
  • General Anesthesia 89%
  • Elderly 42%
  • Mortality 35%
  • Postoperative Complications 30%

• TMU102-AE1-B20

  Hsieh, C.

  8/1/13 → 7/31/16

  Project: B - Project of TMU › g - Research Grants for Newly Hired Faculty

• TMU103-AE1-B29

  Liu, H.

  8/1/15 → 7/31/16

  Project: B - Project of TMU › i - Other (Funded by TMU)

• 發展國際級之「全方位復健研究中心」(第二年)

  Chen, S.

  8/1/15 → 7/31/16

  Project: B - Project of TMU › i - Other (Funded by TMU)

• A Wearable Device Evaluation for Medication Management in Patients Taking Sleep Medicine via Cloud Platform Development( I )

  Li, Y., Jian, W. & Lee, H.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Sleep 100%
  • Wearable technology 35%
  • Health 28%
  • Education 19%
  • Oximeters 11%

• Investigation of the Mechanism of Post-Fracture Immune Dysfunction and the Role of Statin in Its Prevention and Treatment Strategy: from Bench to Bedside

  Lin, J. A.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Wounds and Injuries 100%
  • MicroRNAs 80%
  • Hydroxymethylglutaryl-CoA Reductase Inhibitors 77%
  • 3' Untranslated Regions 65%
  • Immunosuppression 57%

• A Multidisciplinary Study of the Pathophysiology of Blast-Induced Mild Traumatic Brain Injury

  Chiang, Y., Wu, C. & Lee, Y.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Wounds and Injuries 100%
  • Dizziness 86%
  • N-nitrosoiminodiacetic acid 71%
  • Headache 70%
  • Animal Models 59%

• Systemic Analysis on Dynamic Mechanism of Actin Cytoskeleton Organization Regulated Physiological Changes Caused by Physical Stimuli in Mesenchymal Stem Cells

  Ho, J. & Chang, T.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Actins 100%
  • Mesenchymal Stem Cells 72%
  • Proteins 24%
  • Polymerization 22%
  • Microfilament Proteins 19%

• The Potential Role of Glycogen Synthase Kinase-3 in Dengue Virus-Infected Mononuclear Phagocytes

  Lin, C.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Glycogen Synthase Kinase 3 100%
  • Dengue Virus 93%
  • Virus Diseases 47%
  • Interleukin-10 35%
  • Cellular Immunity 28%

• The Role of SUV39H1 in Control of Inflammatory Genes and in Chronic Inflammation of Copd

  Lee, K., Feng, P. & Chuang, H.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Chronic Obstructive Pulmonary Disease 100%
  • Inflammation 60%
  • Blood Cells 33%
  • Histone Deacetylase 2 32%
  • Glucocorticoids 27%

• Cellular and Molecular Mechanisms with Epigenetic Regulation by Histone Deacetylation on Postopratetive Atrial and Pulmonary Vein Arrhythmogenesis

  Chen, Y.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Histone Deacetylases 100%
  • Atrial Fibrillation 85%
  • Pulmonary Veins 63%
  • Calcium 44%
  • Heart Atria 40%

• Study the Function and Regulation of miRNAs in Pancreatic Cancer Progression (II)

  Huang, M.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

• The Protective Effect of PLZF Nuclear Translocation against Advanced Glycation End Product-Induced Endothelial Injury in Diabetes and Its Molecular Mechanism

  Chen, C. & Hsu, Y.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Promyelocytic Leukemia Zinc Finger Protein 100%
  • Protein Transport 32%
  • Human Umbilical Vein Endothelial Cells 27%
  • Advanced Glycation End Products 26%
  • Autophagy 17%

• Genomic, Epigenomic and Epiproteomic Analysis of Etk/Bmx Traumatic Brain Injury

  Chen, K., Chiang, Y. & Wu, C.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Traumatic Brain Injury 100%
  • Protein Kinases 15%
  • Epigenomics 14%
  • Tec protein-tyrosine kinase 14%
  • Inflammation Mediators 10%

• Arsenic Methylation Capacity, Methylenetetrahydrofolate Reductase and Dna Methylation Gene Polymorphisms, Plasma Selenium Concentration and Selenoprotein Gene Polymorphisms and Renal Cell Carcinoma

  Hsueh, Y.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Arsenic 100%
  • Renal Cell Carcinoma 80%
  • Methylenetetrahydrofolate Reductase (NADPH2) 50%
  • Methylation 45%
  • Selenoproteins 39%

• Studying on the Mechanism and Translational Application of Blocking the Protein-Protein Interaction between Galpha-h and PLC-delta1 in Combating Drug-Resistance and Metastasis of Triple-Negative Breast Cancer

  Lin, Y.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Triple Negative Breast Neoplasms 100%
  • Drug Resistance 40%
  • Proteins 28%
  • Peptide Fragments 19%
  • Neoplasm Metastasis 18%

• Molecular Mechanisms of C/EBP-Β Regulates microRNA-16 and Its Clinical Application

  Chen, H.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • MicroRNAs 100%
  • Acute Kidney Injury 78%
  • Transcription Factors 68%
  • Reperfusion Injury 17%
  • Kidney 14%

• To See Is to Believe- Visualization of the Spectrum on Chronic Kidney Disease (II)

  Jian, W., Li, Y. & Wu, M.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Health care 100%
  • Data visualization 75%
  • Patient treatment 50%
  • Disease control 49%
  • Health insurance 49%

• The Development and Preclinical Evaluation of a Theronostic Nanovehicle Drug for Treating Acute Myeloid Leukemia and Leukemia Stem Cells (I)

  Yen, Y., Cheng, T. & Wu, A. T.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Leukemia 100%
  • haptoglobin-hemoglobin complex 54%
  • Calicheamicins 53%
  • Neoplasms 49%
  • Multifunctional Nanoparticles 49%

• Investigate the Biological and Prognostic Association of Annexin A2 in Nasopharyngeal Carcinoma

  Chen, C. & Lee, F.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Annexin A2 100%
  • Nasopharyngeal Carcinoma 85%
  • Annexins 40%
  • DC-specific ICAM-3 grabbing nonintegrin 12%
  • Radiotherapy 10%

• Molecular Pathogenesis of Progression of Cerebral toxocariasis into Alzheimer’s-Like Disease Affected by Dysfunctional Regulation from Impaired UPS and ALS That Lead to Aberrant Βeta-Amyloid Generation and Metabolism in Brain

  Fan, C.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Toxocariasis 100%
  • Toxocara canis 75%
  • Proteasome Endopeptidase Complex 60%
  • Ubiquitin 51%
  • Amyloid Precursor Protein Secretases 45%

• The Neuroprotection Effect and Mechanism of Long Non-Coding RNA MALAT1 in Acute Ischemic Stroke

  Chi, N. & Hu, C.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Stroke 100%
  • Long Noncoding RNA 67%
  • Ischemia 47%
  • Untranslated RNA 47%
  • Cell Line 24%

• The Effect of Long Acting GnRH Agonist Treatment on Mitochondrial Function

  Tzeng, C., Hsieh, R. & Kao, S.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • hormone agonists 100%
  • mitochondria 91%
  • pathophysiology 42%
  • granulosa cells 38%
  • agonists 32%

• Novel Roles of Aryl-Hydrocarbon Receptor ((AhR) on Epigenetic and Post-Translational Modification of Cell-Cycle Regulatory Genes and Enos in Vascular Endothelial Cells---The Therapeutic Potential of Resveratrol/Statins

  Juan, S. & Hwang, L.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Aryl Hydrocarbon Receptors 100%
  • Phosphatidylinositol 3-Kinases 25%
  • cdc Genes 24%
  • Epigenomics 22%
  • Umbilical Cord 22%

• Chronic Obstructive Pulmonary Disease Modulate Electrophysiological Properties and Arrhythmogenesis of Pulmonary Vein and Atrium

  Lin, Y.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Chronic Obstructive Pulmonary Disease 100%
  • Atrial Fibrillation 76%
  • Atrial Remodeling 12%
  • Volition 11%
  • Atrial Flutter 10%

• Study the Anti-Tumor Activity of E1A Gene Therapy---Focus on the Function and Biogenesis of microRNA

  Chen, H.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • MicroRNAs 100%
  • Neoplasms 27%
  • Breast Neoplasms 26%
  • Formal Social Control 14%
  • Genetic Therapy 12%

• Effects of Regular Exercise on Emotional Control and Cognitive Function of Prefrontal-Limbic Pathway in Sleep-Deprived Rats---An Analysis by Behavior and Neurostructural Correlates

  Hsu, C. & Chang, H.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Sleep Deprivation 100%
  • Limbic System 76%
  • Cognition 47%
  • Blood-Brain Barrier 46%
  • Electrolytes 35%

• TMU101-AE1-B64

  Fang, S.

  8/1/13 → 7/31/16

  Project: C - Project of Alliance › u - Taipei Medical University Shuang Ho Hospital

• To Identify Whether Ion Conductance Dysfunction Is an Early Electrophsiological Biomarker of Polyneuropathy in Diabetic Patients: a Longitudinal Study of Nerve Excitability in Diabetic Patients

  Sung, J. & Hu, C.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Neural Conduction 100%
  • Diabetic Neuropathies 69%
  • Ions 24%
  • Biomarkers 19%
  • Polyneuropathies 17%

• Role of Organic Anion Transporter in Renal Tubular Injury---A Gateway to Hurt

  Wu, M.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Chronic Renal Insufficiency 100%
  • Organic Anion Transporters 52%
  • Kidney 45%
  • Single Nucleotide Polymorphism 40%
  • Messenger RNA 27%

• HMGA2, a New Target of Thyroid Hormone-Induced Progression in Colorectal Cancers

  Lin, H., Chang, T. & Yen, Y.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • AT-Hook Motifs 100%
  • Thyroid Hormones 75%
  • tetraiodothyroacetic acid 70%
  • Colorectal Neoplasms 43%
  • Catenins 31%

• The Alteration of Inflammatory Reflex and Its Association with Psychotropic Drugs in Bipolar Disorder from Acute Mania to Full Remission

  Tsai, S.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Bipolar Disorder 100%
  • Reflex 82%
  • Cholinergic Agents 32%
  • Psychological Power 21%
  • Antipsychotic Agents 21%

• TMU103-AE1-B30

  Fang, T.

  8/1/15 → 7/31/16

  Project: B - Project of TMU › i - Other (Funded by TMU)

• Electrophysiological Activity and Functional Correlates in Female Pelvic Floor Muscles

  Yang, J., Huang, W. & Yang, S.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • muscles 100%
  • urinary incontinence 51%
  • electromyography 38%
  • muscle contraction 36%
  • testing 5%

• TMU103-AE1-B33

  Wu, D.

  8/1/15 → 7/31/16

  Project: B - Project of TMU › i - Other (Funded by TMU)

• Traumatic Brain Injury Triggers Acute Lung Injury---The Priming Effects Underlying Subsequent Neurological Sequelae and Cross Organ Injuries

  Wang, J.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Traumatic Brain Injury 100%
  • Acute Lung Injury 69%
  • Adult Respiratory Distress Syndrome 16%
  • Brain Injuries 9%
  • Chemokines 9%

• Association Study of Persistent Metabolic Syndrome, Inflammatory Markers, Adipose Markers and Mild Cognitive Decline

  Bai, C. & Hsu, R.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Cognitive Dysfunction 100%
  • Metabolic Syndrome 67%
  • Mental Status and Dementia Tests 50%
  • Thromboplastin 27%
  • Waist Circumference 24%

• Development of Novel Therapeutic Agents for Breast Cancer through Targeting Nicotinic Acetylcholine Receptors.

  Wu, C., Ho, Y. & Lee, C.

  8/1/15 → 7/31/16

  Project: A - Government Institution › c - Ministry of Health and Welfare

  • Resistance 100%
  • Nicotine 97%
  • Acute Toxicity 95%
  • Acetylcholine 85%
  • Drug 83%

• Study of Novel Genes Regulated by Aberrant DNA Methylation and Application in Colon Cancer Treatment

  Lin, R. & Ho, Y.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Neoplasm Genes 100%
  • Methylation 83%
  • Taiwan 82%
  • DNA Methylation 81%
  • Colonic Neoplasms 66%

• Development of Novel Therapeutic Agents for Herceptin Resistance Breast Cancer Cells through Targeting Nicotinic Acetylcholine Receptors

  Lee, C. & Ho, Y.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Breast Neoplasms 100%
  • Trastuzumab 88%
  • Neoplastic Stem Cells 39%
  • Drug Resistance 27%
  • Luciferases 20%

• The Impact of Environmental Change on Spatial and Temporal Variations of Dengue Outbreaks---Toward Dengue Early Warning System

  Chuang, T.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Land use 100%
  • Population dynamics 81%
  • Alarm systems 62%
  • Remote sensing 57%
  • Satellites 42%

• The Role of Inflammatory Gene Polymorphisms on Risk of Post-Stroke Vascular Dementia (I)

  Chiou, H., Chi, N., Lin, H., Wu, C., Hsieh, F., Hu, C. & Hsieh, Y.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Stroke 93%
  • Cognitive Dysfunction 89%
  • Blood Vessels 52%
  • Inflammation 36%
  • Whole Exome Sequencing 16%