College of Medicine

Projects

Projects per year 2010 2013 2014 2015 2016 2017 2018 2019 2020 2021 2022 2026

• 2 Not started
• 245 Active
• 3059 Finished

Projects per year

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• Finished

  甲基乙二醛經ChREBP/SREBP1造成腎小管脂毒性進而調控PGC1/SIRT3導致電子傳遞鏈缺陷之糖尿腎病進展-探討水飛薊素(Silybin)合併Metformin之逆轉潛能

  Chen, K.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 探討腎臟細胞暴露於塑膠微粒和塑膠奈米中誘發自體吞噬作用和增加SREBPs並引起血管內皮細胞滲漏作用之機制(2/3)

  Chiu, H.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• CHRNA7-p38MAPKs axis發炎基因網絡在巨噬細胞極化作用及對脂蛋白(a)引發冠狀動脈細胞痙攣的機制探討(3/3)

  Hung, M.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 利用人工智慧虛擬篩選平台鑑定DNA聚合酶theta之小分子抑制劑和評估其對於轉移型去勢抗性之攝護腺癌的治療效果(3/3)

  Lin, Y.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 探討ACSL1/FASN訊號軸調控脂質代謝重編程在泌尿道上皮癌化學/免疫治療抗性和轉移所扮演的角色與新穎治療策略的開發

  Wu, C.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• Mechanism-Driven and Target-Based Development of Natural Entry Inhibitors for Prophylactic/Therapeutic Treatment against Emerging Flaviviruses

  Lin, L. T.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 發展具化學/光熱複合療效及骨組織修復功能之奈米粒子應用於發生骨轉移之乳癌治療(2/3)

  Mi, F.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 研究慢性阻塞性肺疾病患者特異性血紅素結合蛋白表現型對巨噬細胞極化作用和疾病進展的調節作用(3/3)

  Ho, S.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 發展具有靶向及溶解血栓功能的奈米藥物治療平台(2/2)

  Mi, F.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• Understanding the Regulatory Mechanisms and Crosstalk between Lipocalin 2 and It Receptor, Slc22a17, in Human Prostate Carcinoma Cells

  Tsui, K.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 以經顱交流電刺激治療思覺失調症的隨機對照試驗(1/3)

  Lu, M.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 艾克曼嗜黏蛋白菌和電漿活化水對硫酸葡聚醣鈉誘導的潰瘍性結腸炎的保護作用：從微生物代謝產物和蛋白質以及細胞外泌體中的小分子核醣核酸觀點出發

  Chang, C.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 研究MSN在大腸直腸癌中對病程進展的調控機制和其治療角色

  Wei, P.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 將BTK-ITK途徑作為標靶以克服肺癌治療的抗藥性以及抑制腦轉移的策略(3/3)

  Kuo, K.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• Balance Control and Motor Strategies in the Elderly with Cognitive Impairments: 3d Motion Analysis, and the Development and Efficacy of a Home-Based Wearable Dual-Task Training Device (Year 2 and 3)( II )

  Kuan, Y.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 探討EZH2在嚴重氣喘中媒介纖維化蛋白表現及呼吸道纖維化之機轉(2/3)

  Lin, C.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 辛伐他汀抗腎細胞癌的作用，經由抑制代謝重編程從mTOR、PPAR到RhoA(3/3)

  Juan, S.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 結核菌感染臨床免疫組庫建立:探勘免疫球蛋白於結核菌感染之保護機制與臨床轉譯應用(3/3)

  Tsai, I.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• Etelcalcetide經由調控DUSP4和TRAF3路徑於慢性腎臟疾病-礦物質骨病變可改善硫酸??酚引起的低骨轉換率(1/3)

  Zheng, C.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• Impact of Childhood Trauma Exposure on Social Cognition in Patients with Schizophrenia – Examines the Role of Oxytocin Receptor Gene Polymorphism

  Goh, K. K.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 血中的纖維細胞在嚴重氣喘患者扮演第二型細胞激素嶄新的細胞來源其臨床相關性與調控機制(2/3)

  Kuo, H.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 膠淋巴系統於混合型失智症之角色(2/2)

  Hu, C.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 探討急性肺損傷之精準幹細胞治療策略與臨床應用: 肺部微環境修復之分子與細胞圖譜及其作用機制-臨床級胎盤間葉幹細胞對急性肺損傷/急性呼吸窘迫症之免疫調控與肺組織再生之治療機制(1/3)

  Huang, Y.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 開發具有骨誘導性之溫感性水膠包埋凍乾型富含血小板纖維蛋白並結合人工代用骨複合型材料用於兔子臨界骨缺損之修補(2/3)

  Wong, C.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• The Study of the Therapeutic Mechanisms of Hydrogen Sulfide Protects Aortic Dissection against Ferroptosis through Regulation of Nrf2-Gpx4 Axis

  Lu, H.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 玻尿酸包埋kaempferol的奈米粒子治療膝關節骨性關節炎的研究

  Lee, C.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 副甲狀腺素藉由SFRP2導致動靜脈廔管病變之惡化 – 預防動靜脈廔管不成熟之新治療標的 (第二年延續計畫)

  Liu, C.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• (教學實踐) 虛擬實境置入醫學系大班教學發展研究-以骨骼肌肉系統課程為例

  Chen, S.

  8/1/21 → 7/31/22

  Project: A - Government Institution › d - Ministry of Education

• 利用單細胞定序技術進行細胞轉錄組及表位標誌來解構腎臟損傷,復原及纖維化過程中腎臟單細胞核吞噬細胞系統的角色(1/3)

  Liao, C.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 金屬蛋白?組織抑制劑3之基因多形性與血漿濃度、總尿液砷濃度、紅血球鉛與鎘濃度和血漿硒濃度與慢性腎臟病的相關性

  Hsueh, Y.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 發展一新型藥物作為改善肥胖及肥胖引發糖尿病導致腎病變症候群之轉譯醫學研究(3/3)

  Lin, H.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• Beta 3腎上腺素信號傳導對心律異常的發生：從心室心肌細胞中心臟代謝，氧化壓力和鈣離子恆定的見解

  Hsieh, M.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• Roles of the Hdacs/Sp1-Mediated Microrna-106b~25 Axis in Drug Resistance of Glioblastomas( III )

  Chen, R.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 探討惡性肥胖病人在接受減重手術前後，腸胃道菌叢變化與減重效果、相關疾病改善狀況的關聯性及其調控機制

  Wang, W.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• Explore the Pathophysiology Role of Vascular Endothelial Cell and Adam 17 during Blue Light-Induced Retinopathy, and the Therapeutic Strategy

  Li, C.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 以老藥利尿劑新用為抗骨肉瘤之藥物：利尿劑對於骨肉瘤細胞存活、爬行與代謝之影響

  Su, B.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 後生元和益生菌透過抑制炎症和調節免疫力減輕新生小鼠高氧誘導的肺損傷

  Chen, C.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• The Investigation of Fungal Stat-Regulating Compounds on Retinal Müller and Microglial Functions and Their Therapeutic Profiles in Glaucomatous Neurodegeneration

  Hsiao, G.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• Developing and Analyzing the Target Protein Components of Schistosoma Egg Antigens as a Drug for Inhibiting Lung Inflammation and the Mechanism Research

  Cheng, P.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 青少年期慢性睡眠剝奪對認知、情緒與壓力調適功能之影響：動物模式與人類世代之整合研究-青少年期慢性睡眠剝奪對認知與情緒功能之影響：動物模式之行為與神經內分泌功能變化探討(3/3)

  Yang, C. H.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 慢性腎臟病之日夜週期失序(2/3)

  Wu, M.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 以多重反應監測質譜分析修格連氏症患者血清中之代謝體與其疾病之關聯性的探討

  Chang, Y.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• FGF9在急性腎損傷與發展至慢性腎臟病進程之角色探討(1/3)

  Cheng, C.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• The Mechanisms of Periodontal Pathogen Aggravating the Formation of Abdominal Aortic Aneurysm and the Development of Targeting Therapy

  Lin, F.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 乳癌細胞受體專一性RNA適體奈米質粒誘發第三型玻尿酸合成酵素的抗癌機制探討(2/3)

  Tu, S.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• Investigating the Therapeutic Potential and Molecular Mechanism of Natural Products in Pediatric High-Grade Gliomas

  Chen, C.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• TIGIT 在調節免疫拮抗點抑制劑抗藥性的角色(1/3)

  Feng, P.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• Microplastics and Nanoplastics Exposure Induce Autophagy and Upregulate Srebps in Kidneys and Cause Endothelial Leakiness in Blood Vessels

  Chiu, H.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• The Utilization, Long-Term Trend, and Associated Factors of Traditional Chinese Medicine in Taiwan: a Large-Scale Study with Multiple Samples

  Liao, C.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 探討在慢性腎臟疾病中經由抑制內皮素轉化?調節前列腺素E2受體和自體吞噬作用的治療潛力之機轉(2/3)

  Chiu, H.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology