College of Medical Science and Technology

Projects

Projects per year 2010 2013 2014 2015 2016 2017 2018 2019 2020 2021 2022 2023 2024 2027

• 79 Active
• 1241 Finished

Projects per year

Search results

• Active

  Investigation of the mechanisms of liver-brain axis in psychiatric diseases development post dengue virus infection(1/3)

  Shen, T.-J. (PI)

  2/1/25 → 1/31/26

  Project: A - Government Institution › b - National Science and Technology Council

  • Virus Infection 100%
  • Disease Course 100%
  • Dengue Virus 100%
  • Viral Disease 100%

• 探討脂毒性作為治療子宮肌瘤的潛在靶點：定量蛋白質體學研究

  Huang, T.-C. (PI)

  1/1/25 → 12/31/25

  Project: B - Project of TMU › i - Other (Funded by TMU)

• 以生成式人工智慧模型開發乳癌基因預後分析與藥物篩選平台(1/4)

  Chang, T.-H. (PI)

  1/1/25 → 12/31/25

  Project: B - Project of TMU › i - Other (Funded by TMU)

• 研究IL1RN 和CCL7在M2-like 巨噬細胞分化中的調控作用及對前列腺癌腫瘤微環境中CCL20 驅動的神經內分泌分化的分子機制

  Liu, Y.-N. (PI)

  1/1/25 → 12/31/25

  Project: B - Project of TMU › i - Other (Funded by TMU)

• 臨床深度推論之醫療專用大型語言模型開發及商業化服務計畫

  Li, Y.-C. (PI)

  1/1/25 → 12/31/25

  Project: A - Government Institution › f - Other (Funded by Government)

• 整合代謝基因調控機轉與合成基因電路載體在神經內分泌前列腺癌免疫治療的應用

  Liu, Y.-N. (PI)

  1/1/25 → 12/31/25

  Project: A - Government Institution › a - National Health Research Institutes

• 使用瓜氨酸間α胰蛋白酶抑制劑重鏈3542-556 胜肽之螢光奈米鑽石自旋提升側流免疫感測器用於檢測類風濕性關節炎的開發和驗證

  Lin, C.-Y. (PI)

  1/1/25 → 12/31/25

  Project: B - Project of TMU › i - Other (Funded by TMU)

• 新穎 NLRP3 發炎小體小分子抑制劑用於慢性腎病之研究開發

  Huang, H.-S. (PI)

  1/1/25 → 12/31/25

  Project: B - Project of TMU › i - Other (Funded by TMU)

• 外泌體循環RNA作為肌肉衰老的生物標誌物及介質

  Kung, H.-J. (PI)

  1/1/25 → 12/31/25

  Project: A - Government Institution › a - National Health Research Institutes

• 台灣前列腺癌病患的全外顯子DNA定序研究

  Shao, Y.-H. (PI)

  12/25/24 → 12/30/25

  Project: A - Government Institution › f - Other (Funded by Government)

• Early-Onset Colorectal Cancer Precision Treatment Strategy: Establishing Drug Repurposing Approach Based on Pharmacogenomics and Combining Novel Anoctamin-6 Neutralizing Antibody

  Lee, K.-H. (PI)

  11/1/24 → 10/31/25

  Project: A - Government Institution › b - National Science and Technology Council

• 利用酵母菌生物模式進行粒線體與細胞核交互作用的演化實驗與基因組分析(1/3)

  Jhuang, H.-Y. (PI)

  11/1/24 → 10/31/25

  Project: A - Government Institution › b - National Science and Technology Council

• 新聘教師研究補助

  Jhuang, H.-Y. (PI)

  10/25/24 → 10/24/25

  Project: B - Project of TMU › g - Research Grants for Newly Hired Faculty

• 新聘教師研究補助

  Shen, T.-J. (PI)

  10/25/24 → 10/24/25

  Project: B - Project of TMU › g - Research Grants for Newly Hired Faculty

• 探討乙型轉化生長因子所誘發之miR-31與長鏈非編碼核醣核酸 LncHIFCAR於口腔癌化過程中之致癌協同作用(3/3)

  Shih, J.-W. (PI)

  8/1/24 → 7/31/25

  Project: A - Government Institution › b - National Science and Technology Council

• Evaluating the Mechanism and Therapeutic Potential of Dyrk1/Clk Inhibitors Modulating Mrna Splicing in Human Digestive Cancers( II )

  Pan, S.-L. (PI)

  8/1/24 → 7/31/25

  Project: A - Government Institution › b - National Science and Technology Council

• Study the Impact of Sex-Dimorphic Fgf21 Expression in Gender Differences of Liver Fibrosis

  Liao, Y.-J. (PI)

  8/1/24 → 7/31/25

  Project: A - Government Institution › b - National Science and Technology Council

• 新穎性DYRK1B抑制劑用於胰臟癌之藥理機轉探討與藥物研發(3/3)

  HuangFu, W.-C. (PI)

  8/1/24 → 7/31/25

  Project: A - Government Institution › b - National Science and Technology Council

• Assessing the Prognostic Impact of Gender Differences on the Effectiveness of Digital Health Interventions in Patients with Chronic Kidney Disease

  Huang, C.-W. (PI)

  8/1/24 → 7/31/25

  Project: A - Government Institution › b - National Science and Technology Council

• The Study of Significance of Rab31 Triggering Exocytosis during Epithelial-Mesenchymal Transition (Emt) for Chemoresistance and Clinical Significance of Colorectal Cancer( II )

  Chen, C.-L. (PI)

  8/1/24 → 7/31/25

  Project: A - Government Institution › b - National Science and Technology Council

• Integrative Graph Representation Learning for Precision Oncology: Unraveling Distinct Pathways in Egfr Exon19del and L858r Mutations of Lung Adenocarcinoma

  Lee, Y.-C. G. (PI)

  8/1/24 → 7/31/25

  Project: A - Government Institution › b - National Science and Technology Council

• Characterization of Tead4 as a Master Regulator of Mitochondrial Activities and a Potential Oncogene for Prostate Cancer( Iv )

  Kung, H.-J. (PI)

  8/1/24 → 7/31/25

  Project: A - Government Institution › b - National Science and Technology Council

• Targeting Lncrs Involved in Hnscc Emt and Pemt( III )

  Kung, H.-J. (PI)

  8/1/24 → 7/31/25

  Project: A - Government Institution › b - National Science and Technology Council

• 抑制介白素-1受體拮抗劑 (IL-1Ra) 的抗胰臟癌機制

  Tsai, Y.-C. (PI)

  8/1/24 → 7/31/25

  Project: A - Government Institution › b - National Science and Technology Council

• 探討運動神經元SARM1在漸凍人症的神經軸突退化過程中對許旺細胞與肌肉的影響與機轉(2/2)

  Lin, Y.-L. (PI)

  8/1/24 → 7/31/25

  Project: A - Government Institution › b - National Science and Technology Council

• 探討site-1蛋白酶抑制劑之抗肝癌分子機轉(3/3)

  Yang, P.-M. (PI)

  8/1/24 → 7/31/25

  Project: A - Government Institution › b - National Science and Technology Council

• 利用複製數變異(CNA)與多體學分析探索癌症驅動CNA及其預後相關調控機制之研究(3/3)

  Chang, T.-H. (PI)

  8/1/24 → 7/31/25

  Project: A - Government Institution › b - National Science and Technology Council

• Exploring the Impact of Mitochondrial Dynamic Drp1 Variation on Steroidogenesis and Fertility

  Kao, S.-H. (PI)

  8/1/24 → 7/31/25

  Project: A - Government Institution › b - National Science and Technology Council

• 設計與優化新穎蛋白質激酶抑制劑應用於胰臟癌之療效與機轉探討(3/3)

  Hsu, K.-C. (PI)

  8/1/24 → 7/31/25

  Project: A - Government Institution › b - National Science and Technology Council

• 利用CAR相關的治療策略清除衰老細胞用於緩解老化與老化相關疾病

  Liu, C.-L. (PI)

  8/1/24 → 7/31/25

  Project: A - Government Institution › b - National Science and Technology Council

• To Clarify Γ-Aminobutyric Acid-Mediated Epigenetic Changes Associated with Temozolomide Resistance in Glioblastoma

  Yang, W.-B. (PI)

  8/1/24 → 7/31/25

  Project: A - Government Institution › b - National Science and Technology Council

• 以針對性風險降低策略為年輕世代提供個性化之健康賦權

  Shabbir, S. A. (PI)

  8/1/24 → 7/31/25

  Project: A - Government Institution › b - National Science and Technology Council

• Assessment of Pharmacokinetics/ Pharmacodynamics of Targeting Exosomes in Alf in Animal Model(1/3)

  Wang, A.H.-J. (PI)

  8/1/24 → 7/31/25

  Project: A - Government Institution › b - National Science and Technology Council

• Development and Optimization of an Anti-Ceacam6 Single Domain Antibody-Drug Conjugate to Improve Blood-Brain Barrier Permeability for Brain-Metastasis Cancer Therapy

  Wu, M.-H. (PI)

  8/1/24 → 7/31/25

  Project: A - Government Institution › b - National Science and Technology Council

• The Role of Rnf128 in Muscle Stem Cells, Focusing on Sarcopenia, Muscle Regeneration, and Neuromuscular Junction Remodeling

  Lin, Y.-L. (PI)

  8/1/24 → 7/31/25

  Project: A - Government Institution › b - National Science and Technology Council

• Establishing a Multimodal Personalized Fracture Risk Prediction Model for Dialysis Patients Using Clinical Phenotype and Wearable Data (Continuation for the 2nd & 3rd Yr)

  Huang, C.-W. (PI)

  8/1/24 → 7/31/25

  Project: A - Government Institution › b - National Science and Technology Council

• Investigating Potential Biomarkers and Mechanisms of Hdac6 Inhibitors in the Treatment of Human Lung Adenocarcinoma

  Pan, S.-L. (PI)

  8/1/24 → 7/31/25

  Project: A - Government Institution › b - National Science and Technology Council

• Utilizing Large Language Models and Real-World Data to Enhance Medication Safety: Creating Rxllama

  Yang, H.-C. (PI)

  8/1/24 → 7/31/25

  Project: A - Government Institution › b - National Science and Technology Council

• A Novel Igf-1r Car Msc Exosome-Based Drug Delivery System for Sorafenib-Resistant Hccs: Focusing Safety, Efficacy, Bio-Distribution, and Immune-Omics Molecular Mechanism( I )

  Huang, Y.-H. (PI)

  8/1/24 → 7/31/27

  Project: A - Government Institution › b - National Science and Technology Council

• Empathimeter - Validation, Implementation, and Evaluation(2/2)

  Li, Y.-C. (PI)

  8/1/24 → 7/31/25

  Project: A - Government Institution › b - National Science and Technology Council

• Targeting Glioblastoma Resilience: Role of Progesterone in Enhancing Chemotherapeutic and Immunotherapeutic Responses through Modulating Protein Sialylation

  Hsu, T.-I. (PI)

  8/1/24 → 7/31/25

  Project: A - Government Institution › b - National Science and Technology Council

• Investigation the Expression Prolife and Functional Role of Early Metastasis of Pancreatic Cancer-Associated Gene-Fxyd3 in Regulating of Metastasis and Acidic Microenvironment through Mir31hg-Mir-7-5p/Mir-206-Fxyd3 Axis(2/3)

  Lee, K.-H. (PI)

  8/1/24 → 7/31/25

  Project: A - Government Institution › b - National Science and Technology Council

• 開發神經內分泌分化前列腺癌之次世代免疫治療(2/3)

  Liu, Y.-N. (PI)

  8/1/24 → 7/31/25

  Project: A - Government Institution › b - National Science and Technology Council

• 探討BMX與Wnt/beta-catenin訊息傳遞路徑對腦外傷後認知功能缺失的調控機制(3/3)

  Chen, K.-Y. (PI)

  8/1/24 → 7/31/25

  Project: A - Government Institution › b - National Science and Technology Council

• 研究CHRM4在攝護腺癌腫瘤微環境中驅動抗發炎反應的分子機制及新穎免疫組合療法的開發(3/3)

  Liu, Y.-N. (PI)

  8/1/24 → 7/31/25

  Project: A - Government Institution › b - National Science and Technology Council

• Enhancing Pancreatic Cancer Treatment: Investigating Dl-N2 Nanoparticles Targeting Integrin Αvβ3 for Targeted Therapy and Combination Treatment Strategies

  Lin, H.-Y. (PI)

  8/1/24 → 7/31/25

  Project: A - Government Institution › b - National Science and Technology Council

• The Essential Role of Chemokines and Their Receptors in Neural Network Formation

  Kao, T.-J. (PI)

  8/1/24 → 7/31/25

  Project: A - Government Institution › b - National Science and Technology Council

• Study the Mechanism of Chemokine-Ccl5 and Its Receptors in Neurogenesis and Differentiation.(2/3)

  Chou, S.-Y. (PI)

  8/1/24 → 7/31/25

  Project: A - Government Institution › b - National Science and Technology Council

• A Translational Exploration of Anisomelic Acid'S Potential in Reprogramming Tumor Immune Microenvironment (Time) to Overcome Immune Checkpoint Inhibitor (Ici) Resistance Mediated by Head and Neck Cancer Stem Cells

  Wu, A. T. (PI)

  8/1/24 → 7/31/25

  Project: A - Government Institution › b - National Science and Technology Council

  • Head and Neck Cancer 100%
  • Immunomodulating Agent 100%
  • Malignant Neoplasm 100%
  • Cancer Stem Cell 100%
  • Immune Checkpoint Inhibitor 100%

• Antimicrobial Resistance Genetic Biomarkers: a Pan-Genome-Based Novel Approach for Pinpointing Antimicrobial Resistance Biomarkers from Bacterial Genomic Sequences(3/3)

  Wu, Y.-W. (PI)

  8/1/24 → 7/31/25

  Project: A - Government Institution › b - National Science and Technology Council

  • Antibiotic Resistance 100%
  • Pan-Genome 100%
  • Genetics 100%
  • Genomics 100%