College of Medical Science and Technology

Projects

Projects per year 2010 2013 2014 2015 2016 2017 2018 2019 2020 2021 2022 2024

• 72 Active
• 1020 Finished

Projects per year

Search results

• The Mechanistic Action of DDX3 in Colorectal Tumor Progression

  Lee, H.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Catenins 100%
  • Drug Resistance 26%
  • Neoplasms 25%
  • Colorectal Neoplasms 22%
  • Carcinogenesis 22%

• The Molecular Basis of Senp2 in Regulating Smad4 Sumoylation and Its Functions in Triple Negative Breast Cancer

  Chang, C.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • SUMO-1 Protein 100%
  • Transforming Growth Factor beta 99%
  • Peptide Hydrolases 83%
  • Sumoylation 26%
  • Triple Negative Breast Neoplasms 23%

• The Molecular Basis of SENP2 in Regulating Smad4 Sumoylation and Its Functions in Triple Negative Breast Cancer

  Chang, C.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • SUMO-1 Protein 100%
  • Transforming Growth Factor beta 85%
  • Peptide Hydrolases 78%
  • Sumoylation 22%
  • Triple Negative Breast Neoplasms 20%

• The Molecular Basis of Senp2 in Regulating Smad4 Sumoylation and Its Functions in Triple Negative Breast Cancer(2/3)

  Chang, C.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • SUMO-1 Protein 100%
  • Transforming Growth Factor beta 99%
  • Peptide Hydrolases 83%
  • Sumoylation 26%
  • Triple Negative Breast Neoplasms 23%

• The Pathogenic Role of Posttranslational Modification of Plasma N-Linked Glycoprotein to Rheumatoid Arthritis Combined Sjogren$S Syndrome Was Investigated

  Lin, C.

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Sjogren's Syndrome 100%
  • Rheumatoid Arthritis 73%
  • Post Translational Protein Processing 62%
  • Blood Proteins 19%
  • Proteins 14%

• The Pharmacological Role of a Novel Dyrk1a Inhibitor in Alzheimer'S Disease

  HuangFu, W.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• The Pre-Clinical Assessment of the Anti-Tumor Efficacy of a Protein Vaccine and Mesenchymal Stem Cell Combined Therapy, Using Non-Invasive Molecular Imaging Technology

  Wu, A. T. & Deng, W.

  8/1/11 → 7/31/12

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Vaccines 100%
  • Molecular Imaging 78%
  • Neoplasms 75%
  • Suicide 61%
  • Mesenchymal Stem Cells 59%

• The Pre-Clinical Assessment of the Anti-Tumor Efficacy of a Protein Vaccine and Mesenchymal Stem Cell Combined Therapy, Using Non-Invasive Molecular Imaging Technology

  Wu, A. T.

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Vaccines 100%
  • Molecular Imaging 78%
  • Neoplasms 75%
  • Suicide 61%
  • Mesenchymal Stem Cells 59%

• The Pre-clinical Investigation of the Anticancer Effects of Polysaccharides Extracted from Ulva Prolifera on Colon Cancer

  Deng, W.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Polysaccharide 100%
  • Anticoagulant 14%
  • Nutrient 12%
  • Antineoplastic Agent 10%
  • Antioxidant Agent 8%

• The Regulation of Pml Degradation by Sentrin-Specific Protease 2

  Chang, C.

  11/1/12 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

  • SUMO-1 Protein 100%
  • Ubiquitination 96%
  • Sumoylation 79%
  • Peptide Hydrolases 74%
  • Protein Stability 70%

• Thermodynamic Stability and Folding Kinetics of Membrane Proteins

  Chang, Y.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • protein 100%
  • membrane 79%
  • trapping 76%
  • folding 48%
  • thermodynamics 22%

• Thermodynamic Stability and Folding Kinetics of Membrane Proteins(2/2)

  Chang, Y.

  8/1/18 → 9/30/19

  Project: A - Government Institution › b - Ministry of Science and Technology

  • protein 100%
  • membrane 79%
  • trapping 76%
  • folding 48%
  • thermodynamics 22%

• The Role of CCR5/RANTES in Neurodegeneration

  Chou, S.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Chemokine CCL5 100%
  • Neurons 54%
  • CCR5 Receptors 29%
  • Phosphatidylinositol 3-Kinases 29%
  • Glycogen Synthase Kinase 3 26%

• The Role of Cytoplasmic APe1 in Tumor Malignancy, Drug Resistance and Lung Cancer Prognosis

  Lee, H.

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

  • NF-kappa B 100%
  • Oxidation-Reduction 45%
  • Cell Nucleus Active Transport 44%
  • Lung Neoplasms 37%
  • Neoplasms 36%

• The Role of Ddx3 in Cetuximab Resistance in Kras-Mutated and -Wild-Type Colorectal Cancer ( I )

  Lee, H.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Cetuximab 100%
  • Colorectal Neoplasms 18%
  • Animal Models 10%
  • Phosphatidylinositol 3-Kinases 9%
  • Tumor Burden 8%

• The role of DDX3 in human papillomavirus-infected lung tumorigenesis

  Lee, H.

  8/1/13 → 7/31/14

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Papillomavirus Infections 100%
  • Cisplatin 96%
  • Lung 86%
  • Neoplasms 63%
  • Gastropoda 47%

• The Role of DDX3 in Human Papillomavirus-Infected Lung Tumorigenesis

  Lee, H.

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Papillomavirus Infections 100%
  • Cisplatin 96%
  • Lung 86%
  • Neoplasms 63%
  • Gastropoda 47%

• The Role of Egfr in Prostate Cancer Progression and Combination Therapy

  Liu, Y.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Prostatic Neoplasms 100%
  • ErbB Receptors 75%
  • Berberis 26%
  • Neoplastic Stem Cells 16%
  • Neoplasms 15%

• The Role of EGFR in Prostate Cancer Progression and Combination Therapy

  Liu, Y. & Chen, W.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Prostatic Neoplasms 100%
  • ErbB Receptors 82%
  • Berberis 26%
  • Neoplastic Stem Cells 16%
  • Neoplasms 15%

• The Role of EGFR in Prostate Cancer Progression and Combination Therapy(2/3)

  Liu, Y.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Prostatic Neoplasms 100%
  • ErbB Receptors 82%
  • Berberis 26%
  • Neoplastic Stem Cells 16%
  • Neoplasms 15%

• The Role of Fungal and Bacterial Microbiota in Fungal Sinusitis: Next Generation Sequencing for Fungal and Bacterial Microbiota Evaluation in Fungal Sinusitis

  Chang, T.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• The Role of Galectin-1 in Fibrosis-promoted Liver Cancer Progression

  Wu, M.

  1/1/16 → 12/31/16

  Project: A - Government Institution › a - National Health Research Institutes

  • Galectin 1 100%
  • Liver Neoplasms 33%
  • Myofibroblasts 29%
  • Fibrosis 22%
  • Liver Cirrhosis 19%

• The Role of Galectin-1 in Fibrosis-promoted Liver Cancer Progression

  Wu, M.

  1/1/15 → 12/31/15

  Project: A - Government Institution › a - National Health Research Institutes

  • Galectin 1 100%
  • Liver Neoplasms 33%
  • Myofibroblasts 29%
  • Fibrosis 22%
  • Liver Cirrhosis 19%

• The Role of Galectin-1 in Liver Fibrosis

  Wu, M.

  1/1/13 → 3/31/14

  Project: A - Government Institution › b - Ministry of Science and Technology

• The Role of Galectin-1 in Liver Fibrosis-Promoted Stem-Like Cell Properties and Sorafenib-Refractoriness of Hbv-Related Hepatocellular Carcinoma(2/3)

  Wu, M.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• The Role of Galectin-1 in Liver Fibrosis-Promoted Stem-Like Cell Properties and Sorafenib-Refractoriness of Hbv-Related Hepatocellular Carcinoma(I)(1/3)

  Wu, M.

  8/1/18 → 8/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

• The Role of Galectin-1 in Liver Fibrosis-Promoted Stem-Like Cell Properties and Sorafenib-Refractoriness of Hbv-Related Hepatocellular Carcinoma( III )

  Wu, M.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• The Role of Galectin-3 in Ceacam6 Enhanced Egfr Signaling and Its Implication in Head and Neck Cancer Therapy

  Wu, M.

  8/1/18 → 7/30/20

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Carcinoembryonic Antigen 100%
  • Cell Adhesion Molecules 98%
  • Galectin 3 64%
  • Squamous Cell Carcinoma of Head and Neck 43%
  • Cetuximab 24%

• The Role of Inflammatory Gene Polymorphisms on Risk of Post-Stroke Vascular Dementia (I)

  Chiou, H., Chi, N., Lin, H., Wu, C., Hsieh, F., Hu, C. & Hsieh, Y.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Stroke 93%
  • Cognitive Dysfunction 89%
  • Blood Vessels 52%
  • Inflammation 36%
  • Whole Exome Sequencing 16%

• The Role of Integrins in Fractalkine Signaling in Atopic Dermatits

  Yoshikazu, T.

  9/1/16 → 8/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

• The Role of Intracellular and Extracellular Ubiquitin Machinery in Modulation of Breast Cancer Tumorigenesis, Metastasis and Tumour Microenvironment

  Chang, S.

  8/1/18 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Ubiquitin 100%
  • Tumor Microenvironment 51%
  • Breast Neoplasms 49%
  • Proteasome Endopeptidase Complex 34%
  • Neoplasm Metastasis 23%

• The Role of miR-1 in RAS Mutation Prostate Cancer Metastasis

  Liu, Y.

  1/1/13 → 10/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

• The role of miR-203 and miR-34a in EGFR activation prostate cancer metastasis

  Liu, Y.

  1/1/16 → 12/31/16

  Project: A - Government Institution › a - National Health Research Institutes

  • Prostatic Neoplasms 100%
  • Genes 42%
  • Neoplasm Metastasis 17%
  • Phenotype 11%
  • Bone and Bones 11%

• The role of miR-203 and miR-34a in EGFR activation prostate cancer metastasis

  Liu, Y.

  1/1/14 → 12/31/14

  Project: A - Government Institution › a - National Health Research Institutes

  • Prostatic Neoplasms 100%
  • Protein-Tyrosine Kinases 52%
  • Neoplasm Metastasis 35%
  • erbB-1 Genes 25%
  • Mutation 21%

• The role of miR-203 and miR-34a in EGFR activation prostate cancer metastasis

  Liu, Y.

  1/1/15 → 12/31/15

  Project: A - Government Institution › a - National Health Research Institutes

  • ErbB Receptors 100%
  • Prostatic Neoplasms 30%
  • Neoplasm Metastasis 23%
  • Prostate 15%
  • Down-Regulation 13%

• The Role of Neuropilin-1 Glycosylation in Galectin-1 Induced Activation of Hepatic Stellate Cells and Liver Fibrosis

  Wu, M. & Yang, W.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Galectin 1 100%
  • Neuropilin-1 68%
  • Liver Cirrhosis 28%
  • Platelet-Derived Growth Factor Receptors 24%
  • thiodigalactoside 12%

• The Role of Neuropilin-1 Glycosylation in Galectin-1 Induced Activation of Hepatic Stellate Cells and Liver Fibrosis

  Wu, M.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Galectin 1 100%
  • Neuropilin-1 68%
  • Liver Cirrhosis 28%
  • Platelet-Derived Growth Factor Receptors 24%
  • thiodigalactoside 12%

• The Role of Neuropilin-1 Glycosylation in Galectin-1 Induced Activation of Hepatic Stellate Cells and Liver Fibrosis(3/3)

  Wu, M.

  8/1/16 → 9/30/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Galectin 1 100%
  • Neuropilin-1 68%
  • Liver Cirrhosis 28%
  • Platelet-Derived Growth Factor Receptors 24%
  • thiodigalactoside 12%

• The role of paxillin in tumor malignancy, drug resistance and clinical outcome in lung cancer

  Lee, H.

  1/1/14 → 12/31/14

  Project: A - Government Institution › a - National Health Research Institutes

  • Paxillin 100%
  • Lung Neoplasms 60%
  • Gefitinib 30%
  • gemcitabine 26%
  • Neoplasms 18%

• The role of paxillin in tumor malignancy, drug resistance and clinical outcome in lung cancer

  Lee, H.

  1/1/15 → 12/31/15

  Project: A - Government Institution › a - National Health Research Institutes

  • Paxillin 100%
  • Lung Neoplasms 60%
  • Gefitinib 30%
  • gemcitabine 26%
  • Neoplasms 18%

• The Role of Protein Kinase CK1 and The Mechanism of Inhibitors on Glioblastoma Cells

  Pan, S.

  7/1/20 → 2/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• The Role of Respiratory Rate Variability and Heart Rate Variability in Predicting Adverse Event in the Hemodialysis Patients

  Shabbir, S. A.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Respiratory Rate 100%
  • Vital Signs 48%
  • Heart Rate 42%
  • Renal Dialysis 31%
  • Physiologic Monitoring 15%

• The Role of Sp1-Regulated Neurosteroidogenesis in Glioma Development

  Hsu, T.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Neurosteroids 100%
  • Glioma 74%
  • Glioblastoma 67%
  • Temozolomide 54%
  • Astrocytes 34%

• The Role of Sp1-Regulated Neurosteroidogenesis in Glioma Development(2/2)

  Hsu, T.

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Neurosteroids 100%
  • Glioma 74%
  • Glioblastoma 67%
  • Temozolomide 54%
  • Astrocytes 34%

• The Role of Wnt5a and Hsp90 in the Wnt/Beta-Catenin Signaling Pathway of Colorectal Cancer (I)

  Lee, K.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Catenins 100%
  • Wnt Signaling Pathway 71%
  • Colorectal Neoplasms 58%
  • Adenomatous Polyposis Coli 39%
  • 5-(2,4-dihydroxy-5-isopropylphenyl)-4-(4-morpholin-4-ylmethylphenyl)isoxazole-3-carboxylic acid ethylamide 19%

• The Role of Wnt5a and Hsp90 in the Wnt/Beta-Catenin Signaling Pathway of Colorectal Cancer (II)

  Lee, K.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

• The Role of Wnt5a and Hsp90 in the Wnt/Beta-Catenin Signaling Pathway of Colorectal Cancer( III )

  Lee, K.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

• The Roles of Novel CCCH Zinc Finger Genes on the Regulation of Cell Proliferation and Inflammation

  Liang, Y.

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Pyroptosis 100%
  • Apoptosis 69%
  • Genes 65%
  • Inflammasomes 60%
  • Cell Proliferation 58%

• The Roles of Novel CCCH Zinc Finger Genes on the Regulation of Cell Proliferation and Inflammation

  Liang, Y.

  8/1/13 → 7/31/14

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Pyroptosis 100%
  • Apoptosis 69%
  • Genes 65%
  • Inflammasomes 60%
  • Cell Proliferation 58%

• The Roles of Novel CCCH Zinc Finger Genes on the Regulation of Cell Proliferation and Inflammation

  Liang, Y.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Pyroptosis 100%
  • Apoptosis 69%
  • Genes 65%
  • Inflammasomes 60%
  • Cell Proliferation 58%