College of Medical Science and Technology

Projects

Projects per year 2010 2013 2014 2015 2016 2017 2018 2019 2020 2021 2022 2024

• 73 Active
• 1019 Finished

Projects per year

Search results

• Finished

  Engineering Chimeric Antigen Receptor T-Cells against Immune Checkpoint Inhibitor Pd1 and Pd-L1 for Treating Pancreatic Cancer

  Liu, C.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Chimeric Antigen Receptors 100%
  • T-Lymphocytes 34%
  • Pancreatic Neoplasms 29%
  • Neoplasms 17%
  • atezolizumab 9%

• Thermodynamic Stability and Folding Kinetics of Membrane Proteins

  Chang, Y.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • protein 100%
  • membrane 79%
  • trapping 76%
  • folding 48%
  • thermodynamics 22%

• Investigations on the Cellular Mechanisms of Ccl5 in Memory Formation and Its Role in Alzheimer’s Disease 2/3

  Chou, S.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Chemokine CCL5 100%
  • Alzheimer Disease 79%
  • Memory 30%
  • Neurons 14%
  • Knockout Mice 11%

• Characterize the E3 Ligase Activity of Znf179 and Its Effect on the Proteinopathies of Tdp-43 Protein

  Huang, C.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Ubiquitin-Protein Ligases 100%
  • Amyotrophic Lateral Sclerosis 47%
  • TDP-43 Proteinopathies 45%
  • Frontotemporal Lobar Degeneration 36%
  • Proteins 32%

• Involvement of Genes Encoding Apoptosis Regulatory Pathway in the Pathogenesis of Hyperglycemia in Acute Ischemic Stroke

  Hsieh, Y.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

• Alternative Treatments for Parkinson$S Disease

  Chen, K.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Parkinson Disease 100%
  • Electroacupuncture 33%
  • Substantia Nigra 27%
  • Exercise 22%
  • 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine 21%

• Exploring the Potential Applications of Dna Mimic Protein Saugi in Viral Diseases and Mrsa by Structure-Based Study

  Wang, H.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Uracil-DNA Glycosidase 100%
  • Simplexvirus 47%
  • Staphylococcus aureus 37%
  • vpr Gene Products 35%
  • Human Immunodeficiency Virus Proteins 29%

• The Role of Sp1-Regulated Neurosteroidogenesis in Glioma Development

  Hsu, T.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Neurosteroids 100%
  • Glioma 74%
  • Glioblastoma 67%
  • Temozolomide 54%
  • Astrocytes 34%

• Investigation of the Role and Underlying Mechanism of Methylenetetrahydrofolate Dehydrogenase 2(Mthfd2) in the Cancer Stem Cell Properties and Tumorigenesis of Lung Cancer

  Deng, W.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Methylenetetrahydrofolate Dehydrogenase (NADP) 100%
  • Neoplastic Stem Cells 29%
  • Lung Neoplasms 27%
  • NAD 21%
  • Serine 20%

• Multi-Layer Active Contour Model of Supraspinatus Detection in Should Ultrasound Image

  Lo, C.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Ultrasonics 100%
  • Imaging techniques 44%
  • Tendons 33%
  • Health care 29%
  • Quality control 27%

• Fragment-Based Discovery of First-In-Class Small-Molecule Kinase Inhibitors for Targeted Cancer Therapies( I )( I )

  Huang, H.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Phosphotransferase Inhibitor 100%
  • Antineoplastic Agent 52%
  • Drug 31%
  • Molecule 27%
  • Chemistry 23%

• Molecular and Translational Study of L1cam in Metastatic Castraction Resistant Prostate Cancer (Mcrpc)

  Hsieh, C.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Neural Cell Adhesion Molecule L1 100%
  • Prostatic Neoplasms 37%
  • Radiation 14%
  • Phosphorylation 13%
  • Bone Neoplasms 11%

• The Molecular Basis of Senp2 in Regulating Smad4 Sumoylation and Its Functions in Triple Negative Breast Cancer

  Chang, C.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • SUMO-1 Protein 100%
  • Transforming Growth Factor beta 99%
  • Peptide Hydrolases 83%
  • Sumoylation 26%
  • Triple Negative Breast Neoplasms 23%

• Investigating the Oncogenic Roles of A9-Nicotinic Acetylcholine Receptor Variants on Breast Cancer( I )

  Ho, Y.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

• To Study the Role of Sp1 in Cancer Drug Resistance( II )

  Chuang, J.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

• 外籍看護工對被看護者健康效益及照護提昇研究

  Li, Y.

  7/28/17 → 12/31/18

  Project: A - Government Institution › f - Other (Funded by Government)

• 以小RNA定序策略來鑑定大腸直腸癌幹細胞外吐小體中可作為腫瘤標記之分子標的

  Hwang, W.

  7/1/17 → 2/28/18

  Project: A - Government Institution › b - Ministry of Science and Technology

• 尋找藥物結構、菌種特性與MIC distribution的關聯與預測模型

  Wu, Y.

  7/1/17 → 2/28/18

  Project: A - Government Institution › b - Ministry of Science and Technology

• 以阿茲海默症模型細胞篩選與評估醣苷神經鞘醯胺衍生物之藥效

  Lin, Y.

  7/1/17 → 2/28/18

  Project: A - Government Institution › b - Ministry of Science and Technology

• 以基因剪輯技術(CRISPR/Cas9)應用於費城染色體為標靶之慢性骨髓性白血病治療

  Lee, C.

  7/1/17 → 2/28/18

  Project: A - Government Institution › b - Ministry of Science and Technology

• 探討高尿酸血症(痛風)病人與日後罹患阿茲海默症疾病風險的相關性研究

  Yang, W.

  7/1/17 → 2/28/18

  Project: A - Government Institution › b - Ministry of Science and Technology

• 探討新型benzimidazole衍生物抑制肝癌抗藥性細胞生長的角色

  Liao, Y.

  7/1/17 → 2/28/18

  Project: A - Government Institution › b - Ministry of Science and Technology

• 苦瓜葉抽取物對於腸胃道免疫提昇與降低畜產養殖業抗生素使用模式評估研究

  Liu, J.

  7/1/17 → 12/31/17

  Project: A - Government Institution › e - Council of Agriculture

• EBP1蛋白質對於細胞及病毒IRES的影響及其作用機轉

  Lin, J.

  7/1/17 → 2/28/18

  Project: A - Government Institution › b - Ministry of Science and Technology

• MCPIPs鋅指蛋白家族在人類大腸直腸癌組織的表現及調控Akt訊息傳遞路徑之研究

  Liang, Y.

  7/1/17 → 2/28/18

  Project: A - Government Institution › b - Ministry of Science and Technology

• 組織胺甲基化轉換酵素參與第第二型人類表皮因子受體蛋白穩定性之探討

  Ho, Y.

  7/1/17 → 2/28/18

  Project: A - Government Institution › b - Ministry of Science and Technology

• "First-in-Class"新穎性抗癌藥物ITCH E3 ubiquitinligase 抑制劑之新藥開發

  Yen, Y.

  7/1/17 → 6/30/18

  Project: A - Government Institution › b - Ministry of Science and Technology

• 抗免疫監測點抑制因子PD1 與PDL1的嵌合抗原受體修飾性γδ-T細胞用於治療卵巢癌療效之探討

  Liu, C.

  7/1/17 → 2/28/18

  Project: A - Government Institution › b - Ministry of Science and Technology

• 建立內皮系細胞血管新生篩選平台以識別中心新生血管促進及拮抗因子

  Hwang, W.

  7/1/17 → 2/28/18

  Project: A - Government Institution › b - Ministry of Science and Technology

• 以RNA-seq分析來探討HIV提高non-AIDS-defining malignancies罹患率之分子機制

  Lee, Y. G.

  7/1/17 → 2/28/18

  Project: A - Government Institution › b - Ministry of Science and Technology

• Creating the SUMOylated-factor specific antibody and the application in biochemical analysis

  Chang, C.

  7/1/17 → 2/28/18

  Project: A - Government Institution › b - Ministry of Science and Technology

• 臺北醫學大學萌芽創業推廣計畫

  Yen, Y.

  6/1/17 → 12/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

• Smokefreebrain: Multidisciplinary Tools for Improving the Efficacy of Public Prevention Measures against Smoking( I )

  Shabbir, S. A.

  5/1/17 → 4/30/18

  Project: A - Government Institution › b - Ministry of Science and Technology

• 再生醫學科技發展計畫－全身安全性異體移植策略之細胞治療產品開發:標靶醫療未滿足慢性發炎相關疾病-糖尿病/褥瘡/嚴重燒燙傷之傷口癒合與多發性硬化症(1/3)

  Yen, Y.

  5/1/17 → 4/30/18

  Project: A - Government Institution › b - Ministry of Science and Technology

• 以體學分析策略來鑑定於大腸直腸癌幹細胞外吐小體中可作為腫瘤標記之分子標的

  Hwang, W.

  4/1/17 → 3/31/18

  Project: C - Project of Alliance › n - Yuan's General Hospital

• 研究Etk/Bmx在大黃素對腦損傷的神經保護作用中所扮演之角色

  Chen, K.

  4/1/17 → 3/31/18

  Project: C - Project of Alliance › n - Yuan's General Hospital

• 研究辛二醯基苯胺羥胺酸提升神經保護因子Znf179表達的作用

  Chuang, J.

  4/1/17 → 3/31/18

  Project: C - Project of Alliance › n - Yuan's General Hospital

• 家族遺傳性肌萎縮性脊髓側索硬化症的基因突變在胚胎發育過程中所造成的影響

  Kao, T.

  4/1/17 → 3/31/18

  Project: C - Project of Alliance › n - Yuan's General Hospital

• 建構領航國際之活躍老化監測暨決策支援系統─活躍老化資料倉儲與決策支援系統(104─107年)之需求規劃暨監造管理計畫_106年度後續擴充

  Liu, C.

  3/24/17 → 12/15/17

  Project: A - Government Institution › c - Ministry of Health and Welfare

• 藉由整合多重組學的資料解析與判定人體中未知細菌的基因表現及該細菌在環境中伴演的角色(1/2)

  Wu, Y.

  3/1/17 → 2/28/18

  Project: A - Government Institution › b - Ministry of Science and Technology

• 探討鼻咽癌的標的治療奈米分子雙抗體或配合化學治療的特性

  Chen, C.

  3/1/17 → 2/28/18

  Project: C - Project of Alliance › o - Chi Mei Medical Center

• Health Internet of Things (Hiot) Medicine, Research &Amp; Industry( I )

  Li, Y.

  2/1/17 → 1/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Internet of things 100%
  • Industry 52%
  • Clinical research 33%
  • Wearable technology 26%
  • Data Analytics 26%

• 研究免疫過度激活和腫瘤發生之重要機轉(2/2)

  Chang, S.

  2/1/17 → 10/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

• Investigation of Molecular Mechanisms Governing Cancer Exosomes-Orchestrated Tumor-Host Interaction during Disease Progression.

  Hwang, W.

  2/1/17 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Exosomes 100%
  • Neoplastic Stem Cells 76%
  • Neoplasms 31%
  • Stem Cells 24%
  • Tumor Microenvironment 13%

• PD-L1 在肺癌酪胺酸激酶抑制劑抗藥性之角色

  Lee, H.

  2/1/17 → 1/31/18

  Project: C - Project of Alliance › r - Tung's Taichung MetroHarbor Hospital

• 以白色念珠菌 alpha-enolase 為目標的單株抗體的人源化與其可能的應用

  Yang, Y.

  2/1/17 → 1/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

• 新聘教師研究補助

  Wu, Y.

  1/1/17 → 12/31/17

  Project: B - Project of TMU › g - Research Grants for Newly Hired Faculty

• 使用級聯低同調干涉之表面電漿技術於微小核醣核酸相位感測

  Chang, C.

  1/1/17 → 12/31/17

  Project: C - Project of Alliance › m - National Taiwan University of Science and Technology

• 第二期癌症研究計畫－臺北醫學大學癌症研究中心計畫

  Yen, Y.

  1/1/17 → 12/31/17

  Project: A - Government Institution › c - Ministry of Health and Welfare

• 新聘教師研究補助

  Hsu, T.

  1/1/17 → 12/31/17

  Project: B - Project of TMU › g - Research Grants for Newly Hired Faculty