College of Medical Science and Technology

Projects

Projects per year 2010 2013 2014 2015 2016 2017 2018 2019 2020 2021 2022 2023 2024 2027

• 85 Active
• 1237 Finished

Projects per year

Search results

• Finished

  整合大腦健康指標與多樣生物標記軌跡及多基因風險分數發展精準的中風後認知功能障礙軌跡預測模型

  Hsieh, Y.-C. (PI)

  8/1/23 → 7/31/24

  Project: A - Government Institution › b - National Science and Technology Council

• 裝載GM-CSF及標靶奈米粒子疫苗之水膠複合系統用於原位募集並活化樹突細胞以增強腫瘤特異性免疫反應達到抑制癌症轉移之功效(3/3)

  Pan, W.-Y. (PI)

  8/1/23 → 7/31/24

  Project: A - Government Institution › b - National Science and Technology Council

• Comprehensive Mining and Analyzing the Effects of Microbes on Disease Development through Unsupervised Microbial Genome Clustering Tools(3/3)

  Wu, Y.-W. (PI)

  8/1/23 → 7/31/24

  Project: A - Government Institution › b - National Science and Technology Council

  File

  • Microbial Genome 100%
  • Feature Extraction 100%
  • Disease Course 100%
  • Microorganism 100%
  • Colorectal Carcinoma 83%

• Effects of Solid Lipid Curcumin Particle (Slcp) on Mtor Signaling in Vivo – Searching for a Mechanism-Based Therapeutic Strategy for Epilepsy in Tuberous Sclerosis Complex (Tsc)(3/3)

  Lee, Y.-C. (PI)

  8/1/23 → 7/31/24

  Project: A - Government Institution › b - National Science and Technology Council

  File

  • In Vivo 100%
  • Tuberous Sclerosis 100%
  • Curcumin 100%
  • Everolimus 30%
  • Epileptogenesis 30%

• 小分子結合位相之預測與分析

  Hsu, K.-C. (PI)

  8/1/23 → 7/31/24

  Project: A - Government Institution › f - Other (Funded by Government)

• 靶向MIR31HG/LncHIFCAR 相關分子網絡在胰腺癌轉移和腫瘤微環境的研究－探討長鏈非編碼RNA-MIR31HG/LncHIFCAR在胰臟癌轉移與腫瘤微環境的交互作用以發展反義寡核苷酸為主的治療策略(1/3)

  Chen, H.-Y. (PI)

  8/1/23 → 7/31/24

  Project: A - Government Institution › b - National Science and Technology Council

• 新穎性DYRK1B抑制劑用於胰臟癌之藥理機轉探討與藥物研發(2/3)

  HuangFu, W.-C. (PI)

  8/1/23 → 7/31/24

  Project: A - Government Institution › b - National Science and Technology Council

• 設計與優化新穎蛋白質激酶抑制劑應用於胰臟癌之療效與機轉探討(2/3)

  Hsu, K.-C. (PI)

  8/1/23 → 7/31/24

  Project: A - Government Institution › b - National Science and Technology Council

• 解析頭頸癌上皮可塑之表觀遺傳調控並制定治療策略－靶向頭頸癌中促進上皮細胞間質轉化之miR-31/MIR31HG非編碼RNA基因簇(2/3)

  Shih, J.-W. (PI)

  8/1/23 → 7/31/24

  Project: A - Government Institution › b - National Science and Technology Council

• 利用臨床表型與穿戴式生理量測資料建立多模態透析病人個人化骨鬆骨折風險預測模型

  Huang, C.-W. (PI)

  8/1/23 → 7/31/24

  Project: A - Government Institution › b - National Science and Technology Council

• 開發用於中樞非典型畸形/橫紋肌樣瘤治療的潛在標的並探討其在臨床前試驗的應用(2/3)

  Chang, C.-C. (PI)

  8/1/23 → 7/31/24

  Project: A - Government Institution › b - National Science and Technology Council

• Antimicrobial Resistance Genetic Biomarkers: a Pan-Genome-Based Novel Approach for Pinpointing Antimicrobial Resistance Biomarkers from Bacterial Genomic Sequences(2/3)

  Wu, Y.-W. (PI)

  8/1/23 → 7/31/24

  Project: A - Government Institution › b - National Science and Technology Council

• Study the Mechanism of Chemokine-Ccl5 and Its Receptors in Neurogenesis and Differentiation.(1/3)

  Chou, S.-Y. (PI)

  8/1/23 → 7/31/24

  Project: A - Government Institution › b - National Science and Technology Council

• 以人工智慧判別糖尿病足傷口影像評估其伴隨周邊血管疾病的風險

  Chiu, H.-W. (PI)

  8/1/23 → 7/31/24

  Project: A - Government Institution › b - National Science and Technology Council

• 利用多維度機器學習來預測腦傷患者的預後

  Lin, M.-C. (PI)

  8/1/23 → 7/31/24

  Project: A - Government Institution › b - National Science and Technology Council

• 研究介白素-1受體拮抗劑(IL1RN)在胰臟癌的功能(3/3)

  Tsai, Y.-C. (PI)

  8/1/23 → 7/31/24

  Project: A - Government Institution › b - National Science and Technology Council

• Functional Study of Phytoplasma Phyl1 Interacting Proteins Using Structural and Proteomic Approaches – Stage 2 Study( III )

  Wang, H.-C. (PI)

  8/1/23 → 7/31/24

  Project: A - Government Institution › b - National Science and Technology Council

  File

  • Proteomics 100%
  • Phytoplasma 100%
  • Witch's Broom 33%
  • Regulatory Protein 33%
  • Transcription Factors 33%

• 探討RNA編輯在膠質母細胞瘤的預後和進展所扮演之角色(2/3)

  Chen, C.-C. (PI)

  8/1/23 → 7/31/24

  Project: A - Government Institution › b - National Science and Technology Council

• 運用深度學習演算法分析多國資料庫以預防特發性妊娠疾病之臨床預測和致病反應途徑研發(II)(2/2)

  Su, E.C.-Y. (PI)

  8/1/23 → 7/31/24

  Project: A - Government Institution › b - National Science and Technology Council

• 以多模態人工智慧機器學習區辨發展遲緩與泛自閉症症候群幼兒及結合複合式早療介入成效進行幼兒語言發展預測(2/3)

  Lo, Y.-C. (PI)

  8/1/23 → 7/31/24

  Project: A - Government Institution › b - National Science and Technology Council

• 探討罕見、不確定重要性與常見致病之基因變異對於前列腺癌風險與發病年齡之影響(2/3)

  Shao, Y.-H. (PI)

  8/1/23 → 7/31/24

  Project: A - Government Institution › b - National Science and Technology Council

• 建立Rrm2b基因剔除小鼠模式用以研究中樞神經系統星狀膠質細胞增多症

  Chen, Y.-F. (PI)

  8/1/23 → 7/31/24

  Project: A - Government Institution › b - National Science and Technology Council

• 利用人工智慧及穿戴式偵測儀客觀評量末期癌症病人體能狀態並預測短期預後存活(II)

  Shabbir, S. A. (PI)

  8/1/23 → 7/31/24

  Project: A - Government Institution › b - National Science and Technology Council

• 新穎性DYRK1B抑制劑用於胰臟癌之藥理機轉探討與藥物研發(2/3)

  HuangFu, W.-C. (PI)

  8/1/23 → 7/31/24

  Project: A - Government Institution › b - National Science and Technology Council

• 標靶整合素αvβ3-FAK訊號網絡的膽管癌診療策略開發-以PRS技術平台優化膽管癌的組合療法(3/3)

  Huang, H.-S. (PI)

  8/1/23 → 7/31/24

  Project: A - Government Institution › b - National Science and Technology Council

• Translational Research of Clinical Grade Placenta-Derived Mesenchymal Stem Cell (Pcmsc) Therapy on Post Ali/Ards Lung Fibrosis( III)

  Wu, M.-H. (PI)

  8/1/23 → 7/31/24

  Project: A - Government Institution › b - National Science and Technology Council

• 研發新穎性標的 RNA splicing 抑制劑用於治療消化道癌症之智慧型藥物設計與轉譯研究－探討 DYRK1/CLK 抑制劑於人類消化道癌進行 mRNA splicing 調控機制和治療潛力(1/3)

  Pan, S.-L. (PI)

  8/1/23 → 7/31/24

  Project: A - Government Institution › b - National Science and Technology Council

• 研發新穎性標的 RNA splicing 抑制劑用於治療消化道癌症之智慧型藥物設計與轉譯研究－利用人工智慧與以結構為基礎策略設計與優化新穎DYRK1/CLK抑制劑(1/3)

  Hsu, K.-C. (PI)

  8/1/23 → 7/31/24

  Project: A - Government Institution › b - National Science and Technology Council

• 探討引導受體與配體之間的cis-弱化互動對脊髓運動神經迴路形成的影響(3/3)

  Kao, T.-J. (PI)

  8/1/23 → 7/31/24

  Project: A - Government Institution › b - National Science and Technology Council

• 探討site-1蛋白酶抑制劑之抗肝癌分子機轉(2/3)

  Yang, P.-M. (PI)

  8/1/23 → 7/31/24

  Project: A - Government Institution › b - National Science and Technology Council

• 探討乙型轉化生長因子所誘發之miR-31與長鏈非編碼核醣核酸 LncHIFCAR於口腔癌化過程中之致癌協同作用(2/3)

  Shih, J.-W. (PI)

  8/1/23 → 7/31/24

  Project: A - Government Institution › b - National Science and Technology Council

• To Define the Attributes of a Novel Theranostic Nanoparticle Dl-N2 to Targeted Integrin Αvβ3 Network in Cholangiocarcinoma(3/3)

  Lin, H.-Y. (PI)

  8/1/23 → 7/31/24

  Project: A - Government Institution › b - National Science and Technology Council

  File

  • Integrin 100%
  • Bile Duct Carcinoma 100%
  • Nanoparticle 100%
  • Malignant Neoplasm 40%
  • Cancer Growth 40%

• 探究粒線體衍胜肽對粒線體功能障礙的細胞保護作用(3/3)

  Kao, S.-H. (PI)

  8/1/23 → 7/31/24

  Project: A - Government Institution › b - National Science and Technology Council

• Investigation the Expression Prolife and Functional Role of Early Metastasis of Pancreatic Cancer-Associated Gene-Fxyd3 in Regulating of Metastasis and Acidic Microenvironment through Mir31hg-Mir-7-5p/Mir-206-Fxyd3 Axis(1/3)

  Lee, K.-H. (PI)

  8/1/23 → 7/31/24

  Project: A - Government Institution › b - National Science and Technology Council

• 糖尿病的心血管風險：新穎性抗丙二醛修飾胜肽加成物自體抗體在血漿中的致病角色並導入機器學習以預測第二型糖尿病合併冠狀動脈疾病

  Lin, C.-Y. (PI)

  8/1/23 → 7/31/24

  Project: A - Government Institution › b - National Science and Technology Council

• 探討運動神經元SARM1在漸凍人症的神經軸突退化過程中對許旺細胞與肌肉的影響與機轉(1/2)

  Lin, Y.-L. (PI)

  8/1/23 → 7/31/24

  Project: A - Government Institution › b - National Science and Technology Council

• TNKS / PI31訊息傳遞路徑在TDP-43相關神經病變中調控蛋白酶體之機制(3/3)

  Huang, C.-C. (PI)

  8/1/23 → 7/31/24

  Project: A - Government Institution › b - National Science and Technology Council

• 開發用於中樞非典型畸形/橫紋肌樣瘤治療的潛在標的並探討其在臨床前試驗的應用(2/3)

  Chang, C.-C. (PI)

  8/1/23 → 7/31/24

  Project: A - Government Institution › b - National Science and Technology Council

• 抗核酸抗體結構特徵研究應用於系統性紅斑狼瘡檢測

  Lee, C.-C. (PI)

  8/1/23 → 7/31/24

  Project: A - Government Institution › b - National Science and Technology Council

• 探討BMX與Wnt/beta-catenin訊息傳遞路徑對腦外傷後認知功能缺失的調控機制(2/3)

  Chen, K.-Y. (PI)

  8/1/23 → 7/31/24

  Project: A - Government Institution › b - National Science and Technology Council

• 解析頭頸癌上皮可塑之表觀遺傳調控並制定治療策略－靶向頭頸部鱗狀細胞癌中與上皮細胞間質轉化所相關的長鏈非編碼RNA(2/3)

  Kung, H.-J. (PI)

  8/1/23 → 7/31/24

  Project: A - Government Institution › b - National Science and Technology Council

• 利用複製數變異(CNA)與多體學分析探索癌症驅動CNA及其預後相關調控機制之研究(2/3)

  Chang, T.-H. (PI)

  8/1/23 → 7/31/24

  Project: A - Government Institution › b - National Science and Technology Council

• 探討HMGCS2基因調控酮體生成與能量代謝轉換對抗藥性肝癌之影響(2/2)

  Liao, Y.-J. (PI)

  8/1/23 → 7/31/24

  Project: A - Government Institution › b - National Science and Technology Council

• Investigating potential therapeutic targets of amino acid metabolism in temozolomide -resistance and relapse glioblastoma patients

  Wang, C.-Y. (PI)

  8/1/23 → 7/31/24

  Project: A - Government Institution › b - National Science and Technology Council

  File

  • Metabolic Pathway 100%
  • Temozolomide 100%
  • Amino Acid 100%
  • Glioblastoma 100%
  • Glioblastoma Multiforme 75%

• Empathimeter - Validation, Implementation, and Evaluation(1/2)

  Li, Y.-C. (PI)

  8/1/23 → 7/31/24

  Project: A - Government Institution › b - National Science and Technology Council

• 研發新穎性MAPK8抑制劑用於阿茲海默症治療

  HuangFu, W.-C. (PI)

  7/1/23 → 2/29/24

  Project: A - Government Institution › b - National Science and Technology Council

• 探討新穎TBK1抑制劑對特發性肺纖維化之功效及機轉

  HuangFu, W.-C. (PI)

  7/1/23 → 2/29/24

  Project: A - Government Institution › b - National Science and Technology Council

• 開發具穿透血腦屏障能力之Class IIa組蛋白去乙醯酶選擇性抑制劑

  Wang, A.H.-J. (PI)

  7/1/23 → 2/29/24

  Project: A - Government Institution › b - National Science and Technology Council

• 人類卵巢顆粒細胞中粒線體動態平衡對於類固醇荷爾蒙生成的影響

  Kao, S.-H. (PI)

  7/1/23 → 2/29/24

  Project: A - Government Institution › b - National Science and Technology Council

• 以超高速腦波掃描探討語言發展遲緩幼兒於腦間同步性之神經特徵指標：以親子共讀過程為例

  Lo, Y.-C. (PI)

  7/1/23 → 2/29/24

  Project: A - Government Institution › b - National Science and Technology Council