College of Medical Science and Technology

Projects

Projects per year 2010 2013 2014 2015 2016 2017 2018 2019 2020 2021 2022 2024

• 72 Active
• 1020 Finished

Projects per year

Search results

• 組織胺甲基化轉換酵素參與第第二型人類表皮因子受體蛋白穩定性之探討

  Ho, Y.

  7/1/17 → 2/28/18

  Project: A - Government Institution › b - Ministry of Science and Technology

• 尋找藥物結構、菌種特性與MIC distribution的關聯與預測模型

  Wu, Y.

  7/1/17 → 2/28/18

  Project: A - Government Institution › b - Ministry of Science and Technology

• MCPIPs鋅指蛋白家族在人類大腸直腸癌組織的表現及調控Akt訊息傳遞路徑之研究

  Liang, Y.

  7/1/17 → 2/28/18

  Project: A - Government Institution › b - Ministry of Science and Technology

• 外籍看護工對被看護者健康效益及照護提昇研究

  Li, Y.

  7/28/17 → 12/31/18

  Project: A - Government Institution › f - Other (Funded by Government)

• The Effect of Wnt Signals and Programmed Cell Death on the Organization of Neural Circuit in Spinal Motor Neurons

  Kao, T.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Motor Neurons 100%
  • Wnt Receptors 73%
  • Ephrins 46%
  • Nerve Growth Factors 42%
  • Growth Cones 40%

• Characterize the E3 Ligase Activity of Znf179 and Its Effect on the Proteinopathies of Tdp-43 Protein

  Huang, C.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Ubiquitin-Protein Ligases 100%
  • Amyotrophic Lateral Sclerosis 47%
  • TDP-43 Proteinopathies 45%
  • Frontotemporal Lobar Degeneration 36%
  • Proteins 32%

• Protective Effects Ofα-Lipoic Acid against Renal Fibrosis in Diabetic Mice

  Lee, H.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Thioctic Acid 100%
  • Kidney 53%
  • Lysine 48%
  • Osteopontin 44%
  • Diabetic Nephropathies 39%

• Mechanisms by Which Enterovirus-Host Interactions Form Viral Replication Organelles and Regulate Viral Replication

  Lin, J.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Organelles 100%
  • Enterovirus 53%
  • Intracellular Membranes 29%
  • Host Microbial Interactions 29%
  • Membranes 27%

• Multi-Layer Active Contour Model of Supraspinatus Detection in Should Ultrasound Image

  Lo, C.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Ultrasonics 100%
  • Imaging techniques 44%
  • Tendons 33%
  • Health care 29%
  • Quality control 27%

• Investigation the Molecular Mechanism of Long Non-Coding Rna-Crnde-Regulated Gene Expression and Identification Inhibitors for Crnde or for Molecules Involved Crnde-Regulated Signaling in Colorectal Cancer Cells

  Lee, K.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Colorectal Neoplasms 100%
  • APC Genes 58%
  • Neoplasms 45%
  • Polycomb Repressive Complex 2 42%
  • Ciclopirox 22%

• Drug Discovery and Pharmacological Investigation of Selective Hdac1 and 2 Inhibitors as Novel Anticancer Drugs

  Pan, S.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Histone 100%
  • Antitumor 34%
  • Antineoplastic Agent 33%
  • Drug 29%
  • DNA Sequence 19%

• Investigation of the Novel Role and Underlying Mechanism of Znf179 in Synaptic Trafficking

  Lee, Y.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Zinc Fingers 100%
  • Proteins 45%
  • Endosomes 15%
  • Exocytosis 15%
  • Ubiquitination 14%

• To Investigate the Role of N-Linked Glycosylated Carcinoembryonic Antigen-Related Cell Adhesion Molecule 6 (Ceacam6) in Egf Receptor Signaling and the Implication in Oral Cancer Therapy

  Wu, M.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Carcinoembryonic Antigen 100%
  • Cell Adhesion Molecules 98%
  • ErbB Receptors 71%
  • Glycosylation 38%
  • Neoplasm Metastasis 11%

• Roles of Microrna96 in Tgfβ-Mediated Tumor Progression

  Tsai, Y.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Transforming Growth Factors 100%
  • Neoplasms 26%
  • Prostatic Neoplasms 21%
  • Castration 15%
  • Androgen Receptors 14%

• Studies on the Mechanisms of Histamine N-Methyltransferase (Hnmt)-Mediated Herceptinr Drug-Resistance in Breast Cancer Cells

  Ho, Y.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Histamine N-Methyltransferase 100%
  • Trastuzumab 89%
  • Breast Neoplasms 17%
  • Tissue Array Analysis 9%
  • Gene Expression Profiling 8%

• Systematic Characterization and Analysis of the Landscape and Regulation of Rna Editing in Human Cancers

  Chen, C.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Inosine 100%
  • RNA Editing 90%
  • Adenosine 73%
  • Neoplasms 57%
  • RNA 51%

• Molecular and Translational Study of L1cam in Metastatic Castraction Resistant Prostate Cancer (Mcrpc)

  Hsieh, C.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Neural Cell Adhesion Molecule L1 100%
  • Prostatic Neoplasms 37%
  • Radiation 14%
  • Phosphorylation 13%
  • Bone Neoplasms 11%

• Interaction between Gut and Brain in High-Functioning Autism: from Phenotypes to Specific Imaging Endophenotypes

  Lo, Y.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Autistic Disorder 100%
  • Neuroimaging 45%
  • Brain 45%
  • Probiotics 44%
  • Biomarkers 38%

• Exploring the Potential Applications of Dna Mimic Protein Saugi in Viral Diseases and Mrsa by Structure-Based Study

  Wang, H.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Uracil-DNA Glycosidase 100%
  • Simplexvirus 47%
  • Staphylococcus aureus 37%
  • vpr Gene Products 35%
  • Human Immunodeficiency Virus Proteins 29%

• Integrated Bioinformatics Approaches to Study the Mechanisms and Discover Drugs of Hcv-Induced Type 2 Diabetes Mellitus( I )

  Hsu, K.

  8/1/17 → 7/1/18

  Project: A - Government Institution › b - Ministry of Science and Technology

• 探討長鏈非編碼RNA在癌症代謝中調控的角色(2/3)

  Kung, H.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

• Investigation on Molecular Pathogenic Mechanisms and Therapy for Park14 Using Pla2g6 Knockin Mouse Model

  Yeh, T.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

• 探討組蛋白去甲基酶KDM4作為前列腺癌的新標靶治療－探討組蛋白去甲基酶KDM4A作為前列腺癌的新標靶治療(2/3)

  Kung, H.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

• Investigation of Long Non-Coding Rna on the Tumorigenesis in Human Colorectal Cancer

  Liang, Y.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Long Noncoding RNA 100%
  • MicroRNAs 26%
  • Colorectal Neoplasms 19%
  • Single Nucleotide Polymorphism 17%
  • Nestin 13%

• Investigation of the Role and Underlying Mechanism of Methylenetetrahydrofolate Dehydrogenase 2(Mthfd2) in the Cancer Stem Cell Properties and Tumorigenesis of Lung Cancer

  Deng, W.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Methylenetetrahydrofolate Dehydrogenase (NADP) 100%
  • Neoplastic Stem Cells 29%
  • Lung Neoplasms 27%
  • NAD 21%
  • Serine 20%

• Roles of Hdac6-Mediated Sp1 Deacetylation in the Evolution of Acquired Temozolomide Resistance in Glioblastoma

  Chuang, J.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Histone Deacetylase 6 100%
  • Temozolomide 84%
  • Glioblastoma 54%
  • Vorinostat 26%
  • Methyltransferases 20%

• Investigation of the Molecular Circuit Directing Mtg8-Mediated Angiogenesis during Tumor Progression

  Hwang, W.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

• Study the Roles of Npc2 in the Regulation of Hepatic Stellate Cells Activation and Liver Fibrosis

  Liao, Y.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Liver Cirrhosis 82%
  • Cholesterol 41%
  • Down-Regulation 17%
  • Fetal Proteins 11%
  • Becaplermin 10%

• Engineering Chimeric Antigen Receptor T-Cells against Immune Checkpoint Inhibitor Pd1 and Pd-L1 for Treating Pancreatic Cancer

  Liu, C.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Chimeric Antigen Receptors 100%
  • T-Lymphocytes 34%
  • Pancreatic Neoplasms 29%
  • Neoplasms 17%
  • atezolizumab 9%

• Crystal Structures and Functional Studies of Novel Glycosyltransferases from Staphylococcus Aureus

  Liu, C.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Glycosyltransferases 100%
  • Staphylococcus aureus 64%
  • Fibrin 30%
  • Cathepsin G 22%
  • Minisatellite Repeats 19%

• The Effectiveness of Hormonal Therapy on Prostate Cancer Bone Metastasis Determined by Klf4

  Liu, Y.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

• 藉由虛擬實境提升高齡者身心健康

  Li, Y.

  8/1/17 → 7/31/18

  Project: B - Project of TMU › i - Other (Funded by TMU)

• Fragment-Based Discovery of First-In-Class Small-Molecule Kinase Inhibitors for Targeted Cancer Therapies( I )( I )

  Huang, H.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Phosphotransferase Inhibitor 100%
  • Antineoplastic Agent 52%
  • Drug 31%
  • Molecule 27%
  • Chemistry 23%

• Discovery of Selective Inhibitors for Oncoprotein Kinases

  Hsu, K.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Protein Kinases 100%
  • Phosphotransferases 92%
  • Oncogene Proteins 72%
  • Pharmaceutical Preparations 35%
  • Neoplasms 24%

• 探討人類胎盤蛻膜間葉幹細胞對肝臟纖維化的治療效果：聚焦免疫調節腫瘤壞死基因-α在肝臟星狀細胞的訊息傳遞(先期補助)

  Wu, M.

  8/1/17 → 7/31/18

  Project: A - Government Institution › f - Other (Funded by Government)

• Alternative Treatments for Parkinson$S Disease

  Chen, K.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Parkinson Disease 100%
  • Electroacupuncture 33%
  • Substantia Nigra 27%
  • Exercise 22%
  • 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine 21%

• Investigations on the Cellular Mechanisms of Ccl5 in Memory Formation and Its Role in Alzheimer’s Disease 2/3

  Chou, S.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Chemokine CCL5 100%
  • Alzheimer Disease 79%
  • Memory 30%
  • Neurons 14%
  • Knockout Mice 11%

• Investigation for the Molecular Mechanism Involved in the Expression and Impact of Alternatively-Spliced Srsf3 and Map4k4 Variants on Brown Adipogenesis

  Lin, J.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • serine 100%
  • arginine 95%
  • adipogenesis 82%
  • brown adipose tissue 72%
  • alternative splicing 55%

• Occupation Choices, Work Characteristics, and Career Success of Medical Technology Undergraduates from Gender and Generational Perspectives (K01)

  Liang, Y.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • medical technology 100%
  • bachelor 44%
  • graduate 29%
  • gender role 22%
  • Taiwan 19%

• The Development and Preclinical Evaluation of a Theronostic Nanovehicle Drug for Treating Acute Myeloid Leukemia and Leukemia Stem Cells.( III )

  Yen, Y.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

• The Role of Sp1-Regulated Neurosteroidogenesis in Glioma Development

  Hsu, T.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Neurosteroids 100%
  • Glioma 74%
  • Glioblastoma 67%
  • Temozolomide 54%
  • Astrocytes 34%

• To Study the Role of Sp1 in Cancer Drug Resistance( II )

  Chuang, J.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

• Thermodynamic Stability and Folding Kinetics of Membrane Proteins

  Chang, Y.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • protein 100%
  • membrane 79%
  • trapping 76%
  • folding 48%
  • thermodynamics 22%

• Impact of Electron-Transfer-Flavoprotein Dehydrogenase Mutation on Bioenergetic Metabolism and Muscular Differentiation in Vitro

  Kao, S.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Multiple Acyl Coenzyme A Dehydrogenase Deficiency 100%
  • Electron-Transferring Flavoproteins 89%
  • Mutation 24%
  • Energy Metabolism 19%
  • Fatty Acids 18%

• The Role of Egfr in Prostate Cancer Progression and Combination Therapy

  Liu, Y.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Prostatic Neoplasms 100%
  • ErbB Receptors 75%
  • Berberis 26%
  • Neoplastic Stem Cells 16%
  • Neoplasms 15%

• The Molecular Basis of Senp2 in Regulating Smad4 Sumoylation and Its Functions in Triple Negative Breast Cancer

  Chang, C.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • SUMO-1 Protein 100%
  • Transforming Growth Factor beta 99%
  • Peptide Hydrolases 83%
  • Sumoylation 26%
  • Triple Negative Breast Neoplasms 23%

• Disease Trajectories and Its Association with Metabolic Dysfunction of Prostate Cancer Men Following Androgen Deprivation Therapy and the Potential of Pharmacological Medication in Preventing Metastatic Diseases.

  Shao, Y.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

• Functional Study of a Novel Long Non-Coding Rna Linat in Colorectal Cancer Progression

  Chen, H.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

• Hmga2, a New Target of Thyroid Hormone-Induced Progression in Colorectal Cancers

  Lin, H.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • AT-Hook Motifs 100%
  • Thyroid Hormones 82%
  • tetraiodothyroacetic acid 76%
  • Colorectal Neoplasms 47%
  • Catenins 34%

• Using Genome-Wide Linkage Analysis and Next Generation Sequencing Approaches to Identify the Genes Responsible for the Familial Colorectal Cancer Type X

  Wang, W.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology