College of Medical Science and Technology

Projects

Projects per year 2010 2013 2014 2015 2016 2017 2018 2019 2020 2021 2022 2024

• 72 Active
• 1020 Finished

Projects per year

Search results

• Engineering Chimeric Antigen Receptor T-Cells against Immune Checkpoint Inhibitor Pd1 and Pd-L1 for Treating Pancreatic Cancer(3/3)

  Liu, C.

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Chimeric Antigen Receptors 100%
  • T-Lymphocytes 34%
  • Pancreatic Neoplasms 29%
  • Neoplasms 17%
  • atezolizumab 9%

• Study of the Roles of Au-Rich Element (Are)-Binding Proteins and Alternative Polyadenylation on the Tumorigenesis of Human Colorectal Cancer(1/3)

  Liang, Y.

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

• Using Machine Learning Technique to Evaluate the Impact of Curcumin on the Brain-Gut Interaction in Patients with Tuberous Sclerosis Complex Comorbid to Autism Spectrum Disorders(1/3)

  Lo, Y.

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

• Involvement of Genes Encoding Apoptosis Regulatory Pathway in the Pathogenesis of Hyperglycemia in Acute Ischemic Stroke

  Hsieh, Y.

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

• Study the Therapeutic Role of Niemann-Pick Type C2 Protein in the Inhibition of Hscs Activation and Liver Fibrosis Treatment

  Liao, Y.

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Liver Cirrhosis 100%
  • Cholesterol 39%
  • Becaplermin 35%
  • Fibrosis 13%
  • Fetal Proteins 12%

• Discovery and Design of Kinase Inhibitors for Cancer Treatment

  Hsu, K.

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Drug 100%
  • 50 Percent Growth Inhibition 63%
  • Disorder 40%
  • Protein 39%
  • Oncogenic 33%

• Studies on the Mechanisms of Histamine N-Methyltransferase (Hnmt)-Mediated Herceptinr Drug-Resistance in Breast Cancer Cells(3/3)

  Ho, Y.

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Histamine N-Methyltransferase 100%
  • Trastuzumab 89%
  • Breast Neoplasms 16%
  • Tissue Array Analysis 9%
  • Gene Expression Profiling 8%

• The Effect of Wnt Signals and Programmed Cell Death on the Organization of Neural Circuit in Spinal Motor Neurons

  Kao, T.

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Motor Neurons 100%
  • Wnt Receptors 73%
  • Ephrins 46%
  • Nerve Growth Factors 42%
  • Growth Cones 40%

• Nano-Diamino-Tetrac (Ndat) Enhances Resveratrol-Induced Anti-Proliferation by Action on the Rrm2 Pathway in Colorectal Cancers

  Lin, H.

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Resveratrol 100%
  • Ribonucleotide 49%
  • Antiproliferative 13%
  • Bellow 10%
  • Stilbenoid 10%

• Characterization of Multiple Functions of Plzf in Brain Development(1/3)

  Lee, Y.

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

• Development of Novel Dyrk1a Inhibitors for the Treatment of Alzheimer'S Disease

  HuangFu, W.

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Dyrk kinase 100%
  • Alzheimer Disease 43%
  • Neurofibrillary Tangles 17%
  • Amyloid beta-Peptides 15%
  • Memory 10%

• Investigation of Astrocytic Cebpd-Regulated Mirnas and Their Effects on Angiogenesis during Neuroinflammation

  Ko, C.

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Alzheimer Disease 100%
  • MicroRNAs 77%
  • Astrocytes 67%
  • Angiogenesis Inducing Agents 41%
  • Endothelial Cells 40%

• Development of Noninvasive Blood Pressure Estimation with Photoplethysmography

  Chiu, H.

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Photoplethysmography 100%
  • Blood pressure 82%
  • Wearable technology 21%
  • Neural networks 19%
  • Intensive care units 8%

• The Role of Sp1-Regulated Neurosteroidogenesis in Glioma Development(2/2)

  Hsu, T.

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Neurosteroids 100%
  • Glioma 74%
  • Glioblastoma 67%
  • Temozolomide 54%
  • Astrocytes 34%

• Investigating the Oncogenic Roles of A9-Nicotinic Acetylcholine Receptor Variants on Breast Cancer(II)(2/3)

  Ho, Y.

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

• Studies of Prostate Cancer Progression after Androgen-Deprivation Therapy and Development of Cancer Immunotherapy via Anti-Inflammation Approaches

  Tsai, Y.

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Androgen Receptors 100%
  • Prostatic Neoplasms 61%
  • Inflammation 54%
  • Androgens 42%
  • Neoplasms 39%

• Investigations on the Cellular Mechanisms of Ccl5 in Memory Formation and Its Role in Alzheimer’s Disease 3/3

  Chou, S.

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Chemokine CCL5 100%
  • Alzheimer Disease 79%
  • Memory 30%
  • Neurons 14%
  • Knockout Mice 11%

• Assessing the Mechanism and Magnifying the Combined Effects of Exercise and Deep Brain Stimulation for Parkinson'S Disease

  Chen, K.

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Deep Brain Stimulation 100%
  • Parkinson Disease 72%
  • Neurodegenerative Diseases 18%
  • Neuroprotection 11%
  • Neuroprotective Agents 10%

• Role of Ribonucleotide Reductase (Rnr) in Skeletal Muscle with Age: the Functionality of Rrm2b in Repair and Regeneration

  Chen, Y.

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Skeletal Muscle 100%
  • Sarcopenia 58%
  • Regeneration 52%
  • Muscles 47%
  • Muscular Diseases 33%

• Artificial Intelligence Grading of Rotator Cuff Tendinopathy Using Real-Time Elastography

  Lo, C.

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Tendons 100%
  • Artificial intelligence 38%
  • Ultrasonics 24%
  • Oils and fats 16%
  • Cost effectiveness 15%

• Study the Toxicity of Chitosan Nanowaste in Freshwater Fishes

  Cheng, C.

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

  • chitosan 100%
  • nanomaterials 86%
  • Danio rerio 53%
  • toxicity 32%
  • nanoparticles 21%

• Investigation of the Curcumin- and Berberine-Mediated Post-Transcriptional Regulation on Ehnancing Brown Adipogenesis

  Lin, J.

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

  • adipogenesis 100%
  • microRNA 84%
  • berberine 64%
  • curcumin 59%
  • amino acid motifs 59%

• Impact of Electron-Transfer-Flavoprotein Dehydrogenase Mutation on Bioenergetic Metabolism and Muscular Differentiation in Vitro

  Kao, S.

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Multiple Acyl Coenzyme A Dehydrogenase Deficiency 100%
  • Electron-Transferring Flavoproteins 89%
  • Mutation 24%
  • Energy Metabolism 19%
  • Fatty Acids 18%

• Carbamylation Modification of Novel Synovial Fluid and Serum Proteins and Its Role of Anti-Carbanylated Protein Autoantibodies in the Clinic Association of Rheumatoid Arthritis Was Investigated

  Lin, C.

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Rheumatoid Arthritis 100%
  • Protein Carbamylation 74%
  • Synovial Fluid 68%
  • Proteins 44%
  • Autoantibodies 41%

• The Effectiveness of Hormonal Therapy on Prostate Cancer Bone Metastasis Determined by Klf4

  Liu, Y.

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

• 腸病毒與宿主間的相互作用對病毒複製複合體形成及病毒複製之作用機轉(3/3)

  Lin, J.

  8/1/18 → 7/31/19

  Project: A - Government Institution › b - Ministry of Science and Technology

• Investigation of Hmga2-Microrna Regulatory Network to Tune Oncogenesis

  Huang, T.

  8/1/18 → 7/31/19

  Project: A - Government Institution › b - Ministry of Science and Technology

  • AT-Hook Motifs 100%
  • MicroRNAs 16%
  • Colorectal Neoplasms 12%
  • Carcinogenesis 9%
  • Neoplasms 7%

• Targeting Kdm4a in Prostate Cancer(III)(3/3)

  Kung, H.

  8/1/18 → 7/31/19

  Project: A - Government Institution › b - Ministry of Science and Technology

• What Is an Insect? Genome Evolution of Insects Relative to Other Pancrustaceans(1/3)

  Chen, C.

  8/1/18 → 7/31/19

  Project: A - Government Institution › b - Ministry of Science and Technology

• Drug Discovery and Pharmacological Investigation of Novel Selective Hdac Inhibitors as Anticancer Drugs(1/3)

  Pan, S.

  8/1/18 → 7/31/19

  Project: A - Government Institution › b - Ministry of Science and Technology

• A Novel Long Non-Coding Rna as a Key Regulator of Tumor Metabolism(3/3)

  Kung, H.

  8/1/18 → 7/31/19

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Pyruvate Kinase 100%
  • Long Noncoding RNA 75%
  • Prostatic Neoplasms 24%
  • Pyruvic Acid 16%
  • Taiwan 15%

• Using Genome-Wide Linkage Analysis and Next Generation Sequencing Approaches to Identify the Genes Responsible for the Familial Colorectal Cancer Type X(2/3)

  Wang, W.

  8/1/18 → 7/31/19

  Project: A - Government Institution › b - Ministry of Science and Technology

• Fragment-Based Discovery of First-In-Class Small-Molecule Kinase Inhibitors for Targeted Cancer Therapies(2/2)

  Huang, H.

  8/1/18 → 7/31/19

  Project: A - Government Institution › b - Ministry of Science and Technology

• 探討長鏈非編碼RNA在癌症代謝中調控的角色(3/3)

  Kung, H.

  8/1/18 → 7/31/19

  Project: A - Government Institution › b - Ministry of Science and Technology

• Investigation of the Cytotoxic Mechanism of Photorhabdus Luminescens Pirapl and Pirbpl Toxins by Using Structural and Proteomic Approaches

  Wang, H.

  8/1/18 → 7/31/19

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Photorhabdus 100%
  • Insecta 30%
  • Aedes 24%
  • toxin V 19%
  • Xenorhabdus 17%

• Computational Analysis of Regulatory Networks of Extracellular Matrix in Endometrial Cancer Development and Discovery of Potential Drugs for Therapy

  Chang, T.

  8/1/18 → 7/31/19

  Project: A - Government Institution › b - Ministry of Science and Technology

• Functional Study of a Novel Long Non-Coding Rna Linat in Colorectal Cancer Progression(2/3)

  Chen, H.

  8/1/18 → 7/31/19

  Project: A - Government Institution › b - Ministry of Science and Technology

• 攝護腺癌之精準代謝治療(1/3)

  Kung, H.

  8/1/18 → 7/31/19

  Project: A - Government Institution › b - Ministry of Science and Technology

• Evolution Haptoglobins as Protein Drugs for Coronary Artery Diseas

  Cheng, T.

  8/1/18 → 7/31/19

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Haptoglobins 100%
  • Coronary Artery Disease 52%
  • Inflammation 27%
  • Nanoparticles 20%
  • Monocytes 19%

• The Role of Galectin-1 in Liver Fibrosis-Promoted Stem-Like Cell Properties and Sorafenib-Refractoriness of Hbv-Related Hepatocellular Carcinoma(I)(1/3)

  Wu, M.

  8/1/18 → 8/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

• Thermodynamic Stability and Folding Kinetics of Membrane Proteins(2/2)

  Chang, Y.

  8/1/18 → 9/30/19

  Project: A - Government Institution › b - Ministry of Science and Technology

  • protein 100%
  • membrane 79%
  • trapping 76%
  • folding 48%
  • thermodynamics 22%

• Study of the Role of L1cam on Neuroendocrine Prostate Cancer Progression

  Hsieh, C.

  8/1/18 → 9/30/19

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Prostatic Neoplasms 100%
  • Neural Cell Adhesion Molecule L1 91%
  • Castration 16%
  • Phenotype 9%
  • RNA-Binding Proteins 5%

• To Study the Role of Sp1 in Cancer Drug Resistance(3/3)

  Chuang, J.

  8/1/18 → 10/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

• Generate Anti-Fibroblast Growth Factor Receptor 2 (Fgfr2) Antibody Drugs and Study on Their Potential Application against Gastric Cancer

  Lee, Y.

  8/1/18 → 10/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

• To Analyze the Risk Assessment of Cumulative Brain Concussion on Football Player Brain Lesions

  Lin, M.

  8/1/18 → 10/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Brain 100%
  • Sports 91%
  • Football 68%
  • Risk assessment 59%
  • Biomarkers 37%

• An in Silico Vaccine Design Method for Allergen Prediction and Ige Epitope Identification Based on Deep Learning Algorithms

  Su, E. C.

  8/1/18 → 10/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Epitopes 100%
  • Allergens 90%
  • Vaccines 63%
  • Immunoglobulin E 48%
  • Deep Learning 43%

• A Novel Lifr Axis in Metabolism Unhinged and Neuroendocrine Differentiation of Prostate Cancer(I)

  Liu, Y.

  8/1/18 → 10/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

• Artificial Intelligence for Earlier and Safer Medicine Worldwide(2/4)

  Li, Y.

  1/1/19 → 10/8/19

  Project: A - Government Institution › b - Ministry of Science and Technology

• 人類胎盤間質幹細胞治療於急性及慢性肺損傷誘發肺纖維化：微環境、免疫調節、基因體/蛋白質體分析與臨床級細胞製備之臨床前轉譯研究-探討人類胎盤間質幹細胞調控肺纖維母細胞活化及肺組織纖維化的角色

  Wu, M.

  1/1/19 → 12/1/19

  Project: A - Government Institution › d - Ministry of Education

• 北醫大的表基因轉譯工作組-在人類幹細胞上的表觀基因工程研究

  Chen, Y.

  1/1/19 → 12/1/19

  Project: A - Government Institution › d - Ministry of Education