College of Medical Science and Technology

Finished

「生醫健康資料商化應用產業需求調查-以藥事服務為主題」採購案

Yang, H.-C. (PI)

10/19/24 → 12/10/24

Project: D - Other Project

透過活體動物高轉移乳癌模式及全基因剔除研究平台（Genome-scale CRISPR- Cas9 Knockout，GeCKO）評估GSDMC基因作為乳癌轉移標靶治療有效性探討

Lee, C.-H. (PI)

7/1/24 → 2/28/25

Project: A - Government Institution › b - National Science and Technology Council

The discovery of a EZH2 inhibitor as a potential cancer treatment for MB and ATRT

Chang, C.-C. (PI)

7/1/24 → 2/28/25

Project: A - Government Institution › b - National Science and Technology Council

利用細菌脂多醣提升臍帶間質幹細胞之免疫調節能力：探討微生物相關發炎疾病的治療機制Enhancing immunomodulation in umbilical cord mesenchymal st

Wang, L.-T. (PI)

7/1/24 → 2/28/25

Project: A - Government Institution › b - National Science and Technology Council

探討Developmentally regulated endothelial cell locus-1（Del-1）在調控肝星狀細胞活化與肝纖維化的角色

Liao, Y.-J. (PI)

7/1/24 → 2/28/25

Project: A - Government Institution › b - National Science and Technology Council

探討結合綠色人工智慧與機器學習技術於電子病歷預測早期肺癌徵兆之成效

Huang, C.-W. (PI)

7/1/24 → 2/28/25

Project: A - Government Institution › b - National Science and Technology Council

研發新穎性 HGK 抑制劑在胰臟癌中之抗癌效用與機轉探討

HuangFu, W.-C. (PI)

7/1/24 → 2/28/25

Project: A - Government Institution › b - National Science and Technology Council

研發新穎高選擇性GSK抑制劑對於胰臟癌治療及藥理機轉探討

Chen, H.-Y. (PI)

7/1/24 → 2/28/25

Project: A - Government Institution › b - National Science and Technology Council

研發新穎性DYRK1B抑制劑並評估其抑制胰臟癌之作用與機轉探討

Liu, Y.-N. (PI)

7/1/24 → 2/28/25

Project: A - Government Institution › b - National Science and Technology Council

研究與 5-Fluorouracil化療藥物的抗藥性相關基因在結直腸癌細胞之上皮間質轉化可塑性中的功能角色

Lee, K.-H. (PI)

7/1/24 → 2/28/25

Project: A - Government Institution › b - National Science and Technology Council

探討高選擇性 HDAC6 抑制劑在膠質母細胞瘤之作用機轉

Pan, S.-L. (PI)

7/1/24 → 2/28/25

Project: A - Government Institution › b - National Science and Technology Council

白色念珠菌檢測試劑與藥物開發——抗 ALS3蛋白抗體之製備與定性

Yang, Y.-Y. (PI)

7/1/24 → 2/28/25

Project: A - Government Institution › b - National Science and Technology Council

利用全基因組剔除研究平台(Genome- Scale CRISPR Knock-Out，GeCKO)篩選 CDC20基因並以CRISPR/Cas9基因剪輯探討其在雙打擊瀰漫性大B細胞瘤(DHL)上抗癌機制

Lee, C.-H. (PI)

7/1/24 → 2/28/25

Project: A - Government Institution › b - National Science and Technology Council

利用XGBoost機器學習模型預測在不同基因組成的屎腸球菌對五種常用抗生素藥物之抗藥性與MIC數值

Wu, Y.-W. (PI)

7/1/24 → 2/28/25

Project: A - Government Institution › b - National Science and Technology Council

評估 ChatGPT 在心血管疾病的藥物諮詢方面的效用

Li, Y.-C. (PI)

7/1/24 → 2/28/25

Project: A - Government Institution › b - National Science and Technology Council

How MALAT-1 Regulate Immune Response and Stemness in Ovarian Tumor Microenvironment

Liu, C.-L. (PI)

7/1/24 → 2/28/25

Project: A - Government Institution › b - National Science and Technology Council

探討腦源性神經營養因子在治療誘導的神經內分泌前列腺癌的免疫抑制功能

Liu, Y.-N. (PI)

7/1/24 → 2/28/25

Project: A - Government Institution › b - National Science and Technology Council

針對機器學習特徵選取演算法選出的與抗藥性高度相關的未知功能基因進行跨物種基因比較分析

Wu, Y.-W. (PI)

7/1/24 → 2/28/25

Project: A - Government Institution › b - National Science and Technology Council

新穎性DDR1抑制劑對神經膠質母細胞瘤之效用評估與機轉分析

Pan, S.-L. (PI)

7/1/24 → 2/28/25

Project: A - Government Institution › b - National Science and Technology Council

建立人工智慧模型預測新穎性TBK1抑制劑與探討其抗發炎機轉

Hsu, K.-C. (PI)

7/1/24 → 2/28/25

Project: A - Government Institution › b - National Science and Technology Council

Transforming Drug Screening for Chemotherapy-Induced Peripheral Neuropathy: the 3d Dual-Layer Hydrogel Co-Culture System and Organoid Technology( I )

Sung, S.-Y. (PI)

6/1/24 → 5/31/25

Project: A - Government Institution › b - National Science and Technology Council

Therapeutic Role of Umbilical Cord Mesenchymal Stem Cells by Modulating Pulmonary Macrophages in Poly I:C-Induced Pneumonia Mimicking Virus-Mediated Acute Respiratory Distress Syndrome

Wang, L.-T. (PI)

5/1/24 → 4/30/25

Project: A - Government Institution › b - National Science and Technology Council

臺歐盟國合計畫－透過基於人工智慧的健康風險評估以鼓勵青少年之行為改變(1/3)

Shabbir, S. A. (PI)

5/1/24 → 4/30/25

Project: A - Government Institution › b - National Science and Technology Council

探討長鏈非編碼核糖核酸MIR31HG調控胰臟癌細胞外基質重塑之作用

Yang, P.-M. (PI)

3/1/24 → 2/28/25

Project: C - Project of Alliance › o - Chi Mei Medical Center

新型奈米工程多標靶小分子抑制劑治療頭頸鱗狀細胞癌的臨床前開發

Huang, H.-S. (PI)

3/1/24 → 3/31/25

Project: C - Project of Alliance › s - Shin Kong Wu Ho-Su Memorial Hospital

跨機構合作的癌症轉譯研究計畫-建立台灣攝護腺癌治療新模式：精進診斷、提升品質和延長生命(第3年)

Kung, H.-J. (PI)

1/1/24 → 12/31/24

Project: A - Government Institution › c - Ministry of Health and Welfare

探討認知與精神障礙之細胞與分子機制並發展治療策略-以結節性硬化症為例

Lee, Y.-C. (PI)

1/1/24 → 12/31/24

Project: B - Project of TMU › h - Higher Education Sprout Project

外泌體循環RNA作為肌肉衰老的生物標誌物及介質

Kung, H.-J. (PI)

1/1/24 → 12/31/24

Project: A - Government Institution › a - National Health Research Institutes

人類生命週期和疾病對前額葉皮質反應的影響與相對應神經調節策略的開發

Lo, Y.-C. (PI)

1/1/24 → 12/31/24

Project: B - Project of TMU › h - Higher Education Sprout Project

浪潮之下：探究海綿衍生物對卵巢癌的抗癌潛力

Huang, T.-C. (PI)

1/1/24 → 12/31/24

Project: B - Project of TMU › i - Other (Funded by TMU)

受石斑魚虹彩病毒(grouper iridovirus, GIV)誘導表現的點帶石斑魚CC趨化素EcSCYA102/103/116/118之免疫功能鑑定

Wang, H.-C. (PI)

1/1/24 → 12/31/24

Project: C - Project of Alliance › l - National Taiwan Ocean University

T-Star Center Ⅰ：台灣癌症尖端研究中心(1/5)

Kung, H.-J. (PI)

1/1/24 → 3/31/25

Project: A - Government Institution › b - National Science and Technology Council

創新性評估化療引發周邊神經病變的藥物研發：3D雙層水凝膠類器官培養系統技術開發

Sung, S.-Y. (PI)

1/1/24 → 12/31/24

Project: B - Project of TMU › h - Higher Education Sprout Project

ZBTB46-PCK1訊息傳遞調控前列腺癌進展的分子機轉及治療意義

Liu, Y.-N. (PI)

1/1/24 → 12/31/24

Project: A - Government Institution › a - National Health Research Institutes

肺癌基因人工智慧早期預防與藥物預後平台開發(4/4)

Chang, T.-H. (PI)

1/1/24 → 12/31/24

Project: B - Project of TMU › i - Other (Funded by TMU)

新聘教師研究補助

Wang, L.-T. (PI)

11/1/23 → 10/31/24

Project: B - Project of TMU › g - Research Grants for Newly Hired Faculty

Establishment of Neurological Disease Pathogenesis Linked with Mis-Metabolsm of Dendritic Spinogenesis Related Mrnas That Are Co-Regulated by Tdp-43 and Fmrp: a Search for New Drug Targets

Pritha, M. (PI)

9/1/23 → 7/31/24

Project: A - Government Institution › b - National Science and Technology Council

Investigating the Anti-Cancer Mechanism of Targeting Udp-Glucuronosyltransferase 2b7 (Ugt-2b7) through Multigenerational Breast Cancer Metastasis Animal Model and Genome-Wide Crispr-Cas9 Knock out (Gecko) Screening Model.

Lee, C.-H. (PI)

8/1/23 → 7/31/24

Project: A - Government Institution › b - National Science and Technology Council

File

Comprehensive Mining and Analyzing the Effects of Microbes on Disease Development through Unsupervised Microbial Genome Clustering Tools(3/3)

Wu, Y.-W. (PI)

8/1/23 → 7/31/24

Project: A - Government Institution › b - National Science and Technology Council

File

新穎性DYRK1B抑制劑用於胰臟癌之藥理機轉探討與藥物研發(2/3)

HuangFu, W.-C. (PI)

8/1/23 → 7/31/24

Project: A - Government Institution › b - National Science and Technology Council

Investigation the Expression Prolife and Functional Role of Early Metastasis of Pancreatic Cancer-Associated Gene-Fxyd3 in Regulating of Metastasis and Acidic Microenvironment through Mir31hg-Mir-7-5p/Mir-206-Fxyd3 Axis(1/3)

Lee, K.-H. (PI)

8/1/23 → 7/31/24

Project: A - Government Institution › b - National Science and Technology Council

A Translational Investigation of Generating Enhanced Mscs and Secretome Using Mfp-Based Proprietary Culture Methods for Dcli Treatment(2/3)

Wu, A. T. (PI)

8/1/23 → 7/31/24

Project: A - Government Institution › b - National Science and Technology Council

Using Multidimensional Machine Learning to Predict Outcomes of Brain-Injured Patients

Lin, M.-C. (PI)

8/1/23 → 7/31/24

Project: A - Government Institution › b - National Science and Technology Council

Unravelling the Prognostic, Regulatory and Therapeutic Potential of Rna Editing in Glioblastoma

Chen, C.-C. (PI)

8/1/23 → 7/31/24

Project: A - Government Institution › b - National Science and Technology Council

Effects of Solid Lipid Curcumin Particle (Slcp) on Mtor Signaling in Vivo – Searching for a Mechanism-Based Therapeutic Strategy for Epilepsy in Tuberous Sclerosis Complex (Tsc)(3/3)

Lee, Y.-C. (PI)

8/1/23 → 7/31/24

Project: A - Government Institution › b - National Science and Technology Council

File

To Define the Attributes of a Novel Theranostic Nanoparticle Dl-N2 to Targeted Integrin Αvβ3 Network in Cholangiocarcinoma(3/3)

Lin, H.-Y. (PI)

8/1/23 → 7/31/24

Project: A - Government Institution › b - National Science and Technology Council

File

Nanocomposite Hydrogel-Delivered Gm-Csf and Targeting Nanoparticle Vaccine That Can Recruit and Activate Dendritic Cells in Situ for Enhancing Tumor-Specific Immune Responses to Inhibit Cancer Metastasis

Pan, W.-Y. (PI)

8/1/23 → 7/31/24

Project: A - Government Institution › b - National Science and Technology Council

開發用於中樞非典型畸形/橫紋肌樣瘤治療的潛在標的並探討其在臨床前試驗的應用(2/3)

Chang, C.-C. (PI)

8/1/23 → 7/31/24

Project: A - Government Institution › b - National Science and Technology Council

Investigating potential therapeutic targets of amino acid metabolism in temozolomide -resistance and relapse glioblastoma patients

Wang, C.-Y. (PI)

8/1/23 → 7/31/24

Project: A - Government Institution › b - National Science and Technology Council

File

A Platform of Appropriate Prescribing in Pregnancy Based on Real World Data: to Train Pharmacist Pioneers and Reduce Inappropriate Medications

Yang, H.-C. (PI)

8/1/23 → 7/31/24

Project: A - Government Institution › b - National Science and Technology Council

College of Medical Science and Technology

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