College of Medical Science and Technology

Projects

Projects per year 2010 2013 2014 2015 2016 2017 2018 2019 2020 2021 2022 2023 2024 2027

• 79 Active
• 1241 Finished

Projects per year

Search results

• Finished

  Effects of Solid Lipid Curcumin Particle (Slcp) on Mtor Signaling in Vivo – Searching for a Mechanism-Based Therapeutic Strategy for Epilepsy in Tuberous Sclerosis Complex (Tsc) (2/3)

  Lee, Y.-C. (PI)

  8/1/22 → 7/31/23

  Project: A - Government Institution › b - National Science and Technology Council

  File

  • In Vivo 100%
  • Tuberous Sclerosis 100%
  • Curcumin 100%
  • Everolimus 30%
  • Epileptogenesis 30%

• Exploring the Activation Mechanism and Neutralization Strategy of the Ahpnd-Causing Toxins Piravp and Pirbvp

  Wang, H.-C. (PI)

  8/1/22 → 7/31/23

  Project: A - Government Institution › b - National Science and Technology Council

• Identification Pklr Metabolic Pathways and Therapeutic Roles in Promoting Neuroendocrine Differentiation of Prostate Cancer

  Liu, Y.-N. (PI)

  8/1/22 → 7/31/23

  Project: A - Government Institution › b - National Science and Technology Council

• Neuronal Function of the Rna-Binding Protein Tdp-43 and Its Dysfunction in Neurodegenerative Diseases (1/3)

  Shen, C.-K. (PI)

  8/1/22 → 7/31/23

  Project: A - Government Institution › b - National Science and Technology Council

• Investigating the Effects of Peripheral Ptx3 Blockade on Alzheimer'S Disease Therapy (Ii)

  Ko, C.-Y. (PI)

  8/1/22 → 7/31/23

  Project: A - Government Institution › b - National Science and Technology Council

• Pathogenic Role of Integrin Αvβ3—Pd-L1—Β-Catenin Axis and Its Therapeutic Strategies in Colorectal Cancer

  Lin, H.-Y. (PI)

  8/1/22 → 7/31/23

  Project: A - Government Institution › b - National Science and Technology Council

• Study the Effects of Hmgcs2 Mediated Ketone Production and Metabolic Shift in Sorafenib-Resistant Hepatocellular Carcinoma (1/2)

  Liao, Y.-J. (PI)

  8/1/22 → 7/31/23

  Project: A - Government Institution › b - National Science and Technology Council

• A Bridg-Driven Smart Authoring Wizard for Clinical Trial Protocols

  Liou, D.-M. (PI)

  8/1/22 → 7/31/23

  Project: A - Government Institution › b - National Science and Technology Council

• The Roles of a Novel Lncrna Linat in Regulating Tgf-Beta Signaling Dynamics and Tumor Malignancies

  Chen, H.-Y. (PI)

  8/1/22 → 7/31/23

  Project: A - Government Institution › b - National Science and Technology Council

• Functional Study of Phytoplasma Phyl1 Interacting Proteins Using Structural and Proteomic Approaches – Stage 2 Study( II )

  Wang, H.-C. (PI)

  8/1/22 → 7/31/23

  Project: A - Government Institution › b - National Science and Technology Council

  • Phytoplasma 100%
  • Proteomics 100%

• 經由垂直性群組研究與分子調控機制探討腸道代謝物和腸道菌叢對慢性腎病進程之影響

  Lin, J.-C. (PI)

  8/1/22 → 7/31/23

  Project: B - Project of TMU › i - Other (Funded by TMU)

• Predicting Language Development and Classification in Toddlers with Developmental Delays and Autism Spectrum Disorders by Applying Multimodal Data to Artificial Intelligence/Machine Learning and Combining the Therapeutic Efficacy of Early Intervention (1/3)

  Lo, Y.-C. (PI)

  8/1/22 → 7/31/23

  Project: A - Government Institution › b - National Science and Technology Council

• 111 年「教育部補助大專校院 STEM 領域及女性研發人才培育計畫」：整合智慧型新藥研發跨領域女性人才培育計畫-以新藥創新創業為例

  Pan, S.-L. (PI)

  8/1/22 → 7/31/23

  Project: A - Government Institution › d - Ministry of Education

• Tgf-Beta-Induced Oncogenic Collaboration of Mir-31 and Lnchifcar Contributes to Oral Tumorigenesis (1/3)

  Shih, J.-W. (PI)

  8/1/22 → 7/31/23

  Project: A - Government Institution › b - National Science and Technology Council

  • microRNA 31 100%
  • Carcinogenesis 100%
  • Liquid Biopsy 33%
  • Predictive Marker 33%
  • Oral Cancer 33%

• TNKS / PI31訊息傳遞路徑在TDP-43相關神經病變中調控蛋白酶體之機制(2/3)

  Huang, C.-C. (PI)

  8/1/22 → 7/31/23

  Project: A - Government Institution › b - National Science and Technology Council

• To Define the Attributes of a Novel Theranostic Nanoparticle Dl-N2 to Targeted Integrin Αvβ3 Network in Cholangiocarcinoma(2/3)

  Lin, H.-Y. (PI)

  8/1/22 → 7/31/23

  Project: A - Government Institution › b - National Science and Technology Council

• Mechanistic Investigation of Anticancer Activity of the Site-1 Protease Inhibitor against Hepatocellular Carcinoma (1/3)

  Yang, P.-M. (PI)

  8/1/22 → 7/31/23

  Project: A - Government Institution › b - National Science and Technology Council

• Translational Research of Clinical Grade Placenta-Derived Mesenchymal Stem Cell (Pcmsc) Therapy on Post Ali/Ards Lung Fibrosis( II )

  Wu, M.-H. (PI)

  8/1/22 → 7/31/23

  Project: A - Government Institution › b - National Science and Technology Council

• To Establish a Phenotypic Response Surface (Prs) Technology Platform to Optimize Combination Therapy for Cholangiocarcinoma.( II )

  Huang, H.-S. (PI)

  8/1/22 → 7/31/23

  Project: A - Government Institution › b - National Science and Technology Council

• The Effect of Guidance Receptor/Ligand Cis-Attenuation on Neural Circuit Assembly in Spinal Motor Neurons (2/3)

  Kao, T.-J. (PI)

  8/1/22 → 7/31/23

  Project: A - Government Institution › b - National Science and Technology Council

• Investigation of the Effects of Ccl5 Mediated Neuronal Energy Metabolism on Hippocampal Neurogenesis and Memory Formation under Normal and Alzehemier’S Disease Conditions

  Chou, S.-Y. (PI)

  8/1/22 → 7/31/23

  Project: A - Government Institution › b - National Science and Technology Council

• PAR1嵌合抗體T細胞及T調節細胞在臨床治療上的多功能應用

  Liu, C.-L. (PI)

  8/1/22 → 7/31/23

  Project: B - Project of TMU › i - Other (Funded by TMU)

• Design and Optimization of Novel Protein Kinase Inhibitors for Pancreatic Cancer Treatment and Mechanism Investigation (1/3)

  Hsu, K.-C. (PI)

  8/1/22 → 7/31/23

  Project: A - Government Institution › b - National Science and Technology Council

• The Drug Discovery and Pharmacological Role for Novel Dyrk1b Inhibitors in Pancreatic Cancer (1/3)

  HuangFu, W.-C. (PI)

  8/1/22 → 7/31/23

  Project: A - Government Institution › b - National Science and Technology Council

• A Platform of Appropriate Prescribing in Pregnancy Based on Real World Data: to Train Pharmacist Pioneers and Reduce Inappropriate Medications (2/3)

  Yang, H.-C. (PI)

  8/1/22 → 7/31/23

  Project: A - Government Institution › b - National Science and Technology Council

• Antimicrobial Resistance Genetic Biomarkers: a Pan-Genome-Based Novel Approach for Pinpointing Antimicrobial Resistance Biomarkers from Bacterial Genomic Sequences (1/3)

  Wu, Y.-W. (PI)

  8/1/22 → 7/31/23

  Project: A - Government Institution › b - National Science and Technology Council

  • Antibiotic Resistance 100%
  • Pan-Genome 100%
  • Genetics 100%
  • Genomics 100%

• 111 年「教育部補助大專校院 STEM 領域及女性研發人才培育計畫」：次世代遠距醫療人才培育計畫

  Yang, H.-C. (PI)

  8/1/22 → 7/31/23

  Project: A - Government Institution › d - Ministry of Education

• Nanocomposite Hydrogel-Delivered Gm-Csf and Targeting Nanoparticle Vaccine That Can Recruit and Activate Dendritic Cells in Situ for Enhancing Tumor-Specific Immune Responses to Inhibit Cancer Metastasis

  Pan, W.-Y. (PI)

  8/1/22 → 7/31/23

  Project: A - Government Institution › b - National Science and Technology Council

• Development of a Sesquiterpene Lactone, Antrocin, as a Therapeutic Lead Compound and Its Nano-Enabled Form for Targeting Proneural-To-Mesenchymal Transition in Glioma Stem Cells

  Wu, A. T. (PI)

  8/1/22 → 7/31/23

  Project: A - Government Institution › b - National Science and Technology Council

  • Sesquiterpene Lactone 100%
  • Lead Compound 100%
  • Glioma Stem Cell 100%
  • Immune Escape 100%

• Tnks/Pi31 Signal Cascade in the Spectrum of Proteasome Regulation under Tdp-43 Neuropathies(2/3)

  Huang, C.-C. (PI)

  8/1/22 → 7/31/23

  Project: A - Government Institution › b - National Science and Technology Council

• Preclinical Development and Evaluation of Novel Nano-Engineered Multi-Target Small Molecule Inhibitor Nsc777205 for Metastatic Colorectal Cancer

  Huang, H.-S. (PI)

  8/1/22 → 7/31/23

  Project: A - Government Institution › b - National Science and Technology Council

• Unravelling the Prognostic, Regulatory and Therapeutic Potential of Rna Editing in Glioblastoma (1/3)

  Chen, C.-C. (PI)

  8/1/22 → 7/31/23

  Project: A - Government Institution › b - National Science and Technology Council

• Role and Therapeutic Application of Mesenchymal Stem Cells in Hypoxia-Induced Neuroendocrine Prostate Cancer Progression (2/3)

  Sung, S.-Y. (PI)

  8/1/22 → 7/31/23

  Project: A - Government Institution › b - National Science and Technology Council

• Study the Molecular Mechanism of Chrm4 Driving the Anti-Inflammatory Response in the Tumor Microenvironment of Prostate Cancer and the Development of Novel Combination Immunotherapy( I )

  Liu, Y.-N. (PI)

  8/1/22 → 7/31/23

  Project: A - Government Institution › b - National Science and Technology Council

• Evaluate the Combined Effects of Rare Pathogenic, Uncertain Significance, and Common Germline Variants on the Risk of Prostate Cancer and Age at Onset. (1/3)

  Shao, Y.-H. (PI)

  8/1/22 → 7/31/23

  Project: A - Government Institution › b - National Science and Technology Council

• A Copy Number Alteration (Cna) Research Roadmap Using Multi-Omics Data for Identification of Cna-Derived Cancer Driver Genes and Their Potential Regulatory Mechanisms Associated with Prognosis (1/3)

  Chang, T.-H. (PI)

  8/1/22 → 7/31/23

  Project: A - Government Institution › b - National Science and Technology Council

• 利用聯邦式學習來偵測腦損傷病人之大腦意識

  Lin, M.-C. (PI)

  8/1/22 → 7/31/23

  Project: B - Project of TMU › i - Other (Funded by TMU)

• Development of Natural Product and Its Derivatives as Potential Treatment for Alzheimer’S Disease(2/3)

  Pan, S.-L. (PI)

  8/1/22 → 7/31/23

  Project: A - Government Institution › b - National Science and Technology Council

• Cloud-Based Graph Representation Learning of Biological Pathways with Proteo-Transcriptomics for Cancer Systems Biology

  Lee, Y.-C. G. (PI)

  8/1/22 → 7/31/23

  Project: A - Government Institution › b - National Science and Technology Council

• A Translational Investigation of Generating Enhanced Mscs and Secretome Using Mfp-Based Proprietary Culture Methods for Dcli Treatment( I )

  Wu, A. T. (PI)

  8/1/22 → 7/31/23

  Project: A - Government Institution › b - National Science and Technology Council

  • Secretome 100%
  • Molecular Network 50%

• Development of a Novel Therapeutic Strategy for Triple Negative Breast Cancers (Tnbc) through Targeting Udp-Glucuronosyltransferase 2b7 (Ugt2b7)( III )

  Lee, C.-H. (PI)

  8/1/22 → 7/31/23

  Project: A - Government Institution › b - National Science and Technology Council

• The Role of Fatty Acid Metabolic Reprogramming Associated with Mitochondrial Dna Mutations in the Drug Resistance of Glioblastoma

  Hsu, T.-I. (PI)

  8/1/22 → 7/31/23

  Project: A - Government Institution › b - National Science and Technology Council

• Clinical Prediction and Pathogenesis Pathway Discovery to Prevent Idiopathic Pregnancy Diseases by Deep Learning Algorithms on Multi-Country Databases( II )

  Su, E.C.-Y. (PI)

  8/1/22 → 7/31/23

  Project: A - Government Institution › b - National Science and Technology Council

• 新穎PDI抑制劑誘導鐵死亡之研究

  Liang, Y.-C. (PI)

  7/1/22 → 2/28/23

  Project: A - Government Institution › b - National Science and Technology Council

• 長期暴露低劑量塑化劑對肝癌藥物 （sorafenib）感受性的影響

  Liao, Y.-J. (PI)

  7/1/22 → 2/28/23

  Project: A - Government Institution › b - National Science and Technology Council

• 粒線體衍生肽對於細胞自噬作用的影響

  Kao, S.-H. (PI)

  7/1/22 → 2/28/23

  Project: A - Government Institution › b - National Science and Technology Council

• 研發急性骨髓性白血病的新穎性CDK8抑制劑並以毒理測試評估其安全性

  Pan, S.-L. (PI)

  7/1/22 → 2/28/23

  Project: A - Government Institution › b - National Science and Technology Council

• Characterization of Sleep Disturbance during Disease Progression in Tuberous Sclerosis Complex

  Lee, Y.-C. (PI)

  7/1/22 → 2/28/23

  Project: A - Government Institution › b - National Science and Technology Council

• 探討高密度脂蛋白膽固醇和缺血性中風預後的因果相關性：雙樣本孟德爾隨機化分析

  Hsieh, Y.-C. (PI)

  7/1/22 → 2/28/23

  Project: A - Government Institution › b - National Science and Technology Council

• 以LINE平台作為個人化衛教資訊提供之成效評估：以中高齡透析病患為例

  Huang, C.-W. (PI)

  7/1/22 → 2/28/23

  Project: A - Government Institution › b - National Science and Technology Council