College of Medical Science and Technology

Projects

Projects per year 2010 2013 2014 2015 2016 2017 2018 2019 2020 2021 2022 2023 2024

• 115 Active
• 1081 Finished

Projects per year

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• Active

  新聘教師研究補助

  Wang, L.

  11/1/23 → 10/31/24

  Project: B - Project of TMU › g - Research Grants for Newly Hired Faculty

• 以樹突棘發育相關的mRNA為作用目標，建立由TDP-43和FMRP共同調控 參與 的神經疾病發病機制：藉此尋找新的藥物靶標(3/3)

  Pritha, M.

  9/1/23 → 7/31/24

  Project: A - Government Institution › b - National Science and Technology Council

• 一個基於骨傳導收發音型式的泛用化智慧醫療設計

  Su, E. C.

  8/1/23 → 12/31/23

  Project: B - Project of TMU › h - Higher Education Sprout Project

• 研究CHRM4在攝護腺癌腫瘤微環境中驅動抗發炎反應的分子機制及新穎免疫組合療法的開發(2/3)

  Liu, Y.

  8/1/23 → 7/31/24

  Project: A - Government Institution › b - National Science and Technology Council

• 解析頭頸癌上皮可塑之表觀遺傳調控並制定治療策略－靶向頭頸部鱗狀細胞癌中與上皮細胞間質轉化所相關的長鏈非編碼RNA(2/3)

  Kung, H.

  8/1/23 → 7/31/24

  Project: A - Government Institution › b - National Science and Technology Council

• 靶向MIR31HG/LncHIFCAR 相關分子網絡在胰腺癌轉移和腫瘤微環境的研究－探討胰臟癌早期轉移基因-FXYD3於MIR31HG-miR-7-5p/miR-206-FXYD3訊息途徑中調控胰臟癌的轉移與酸性微環境的角色(1/3)

  Lee, K.

  8/1/23 → 7/31/24

  Project: A - Government Institution › b - National Science and Technology Council

• 探討急性肺損傷之精準幹細胞治療策略與臨床應用: 肺部微環境修復之分子與細胞圖譜及其作用機制-臨床級胎盤間葉幹細胞對急性肺損傷/急性呼吸窘迫症後肺纖維化治療效果的轉譯研究(3/3)

  Wu, M.

  8/1/23 → 7/31/24

  Project: A - Government Institution › b - National Science and Technology Council

• 整合大腦健康指標與多樣生物標記軌跡及多基因風險分數發展精準的中風後認知功能障礙軌跡預測模型

  Hsieh, Y.

  8/1/23 → 7/31/24

  Project: A - Government Institution › b - National Science and Technology Council

• 利用臨床表型與穿戴式生理量測資料建立多模態透析病人個人化骨鬆骨折風險預測模型

  Huang, C.

  8/1/23 → 7/31/24

  Project: A - Government Institution › b - National Science and Technology Council

• 利用人工智慧及穿戴式偵測儀客觀評量末期癌症病人體能狀態並預測短期預後存活(II)

  Shabbir, S. A.

  8/1/23 → 7/31/24

  Project: A - Government Institution › b - National Science and Technology Council

• 探討RNA編輯在膠質母細胞瘤的預後和進展所扮演之角色(2/3)

  Chen, C.

  8/1/23 → 7/31/24

  Project: A - Government Institution › b - National Science and Technology Council

• TNKS / PI31訊息傳遞路徑在TDP-43相關神經病變中調控蛋白酶體之機制(3/3)

  Huang, C.

  8/1/23 → 7/31/24

  Project: A - Government Institution › b - National Science and Technology Council

• 靶向MIR31HG/LncHIFCAR 相關分子網絡在胰腺癌轉移和腫瘤微環境的研究－探討長鏈非編碼RNA-MIR31HG/LncHIFCAR在胰臟癌轉移與腫瘤微環境的交互作用以發展反義寡核苷酸為主的治療策略(1/3)

  Chen, H.

  8/1/23 → 7/31/24

  Project: A - Government Institution › b - National Science and Technology Council

• 由細菌泛基因體預測與尋找抗藥性細菌的基因體生物標記(2/3)

  Wu, Y.

  8/1/23 → 7/31/24

  Project: A - Government Institution › b - National Science and Technology Council

• 運用深度學習演算法分析多國資料庫以預防特發性妊娠疾病之臨床預測和致病反應途徑研發(II)(2/2)

  Su, E. C.

  8/1/23 → 7/31/24

  Project: A - Government Institution › b - National Science and Technology Council

• 探討site-1蛋白酶抑制劑之抗肝癌分子機轉(2/3)

  Yang, P.

  8/1/23 → 7/31/24

  Project: A - Government Institution › b - National Science and Technology Council

• 解析頭頸癌上皮可塑之表觀遺傳調控並制定治療策略－靶向頭頸癌中促進上皮細胞間質轉化之miR-31/MIR31HG非編碼RNA基因簇(2/3)

  Shih, J.

  8/1/23 → 7/31/24

  Project: A - Government Institution › b - National Science and Technology Council

• 研發新穎性標的 RNA splicing 抑制劑用於治療消化道癌症之智慧型藥物設計與轉譯研究－利用人工智慧與以結構為基礎策略設計與優化新穎DYRK1/CLK抑制劑(1/3)

  Hsu, K.

  8/1/23 → 7/31/24

  Project: A - Government Institution › b - National Science and Technology Council

• 研究趨化因子-CCL5及其受體在神經新生和分化中的作用機制(1/3)

  Chou, S.

  8/1/23 → 7/31/24

  Project: A - Government Institution › b - National Science and Technology Council

• 以定量蛋白質體學方法探討SOAT、油滴以及脂肪細胞分泌因子在大腸癌致病機轉所扮演的角色(2/3)

  Huang, T.

  8/1/23 → 7/31/24

  Project: A - Government Institution › b - National Science and Technology Council

• 建立Rrm2b基因剔除小鼠模式用以研究中樞神經系統星狀膠質細胞增多症

  Chen, Y.

  8/1/23 → 7/31/24

  Project: A - Government Institution › b - National Science and Technology Council

• 探究粒線體衍胜肽對粒線體功能障礙的細胞保護作用(3/3)

  Kao, S.

  8/1/23 → 7/31/24

  Project: A - Government Institution › b - National Science and Technology Council

• 標靶整合素αvβ3-FAK訊號網絡的膽管癌診療策略開發-以PRS技術平台優化膽管癌的組合療法(3/3)

  Huang, H.

  8/1/23 → 7/31/24

  Project: A - Government Institution › b - National Science and Technology Council

• 以真實世界資料建構懷孕處方適當性平台 : 輔以種子藥師培育，降低不適當用藥(3/3)

  Yang, H.

  8/1/23 → 7/31/24

  Project: A - Government Institution › b - National Science and Technology Council

• 以跨世代活體高轉移乳癌模型與全基因組剔除(GeCKO)分析模式探討尿苷雙磷酸葡萄糖醛酸基轉移酶2B7(UGT2B7)標靶抗癌機制

  Lee, C.

  8/1/23 → 7/31/24

  Project: A - Government Institution › b - National Science and Technology Council

• 探討BMX與Wnt/beta-catenin訊息傳遞路徑對腦外傷後認知功能缺失的調控機制(2/3)

  Chen, K.

  8/1/23 → 7/31/24

  Project: A - Government Institution › b - National Science and Technology Council

• 標靶整合素αvβ3-FAK訊號網絡的膽管癌診療策略開發-標靶膽管癌整合素αvβ3訊號網絡的新型診療性奈米微脂體DL-N2之研究(3/3)

  Lin, H.

  8/1/23 → 7/31/24

  Project: A - Government Institution › b - National Science and Technology Council

• 哺乳類動物DNA甲基化酶的新功能─去DNA甲基化活性的生理角色, 調控機制, 與轉譯研究(3/3)

  Shen, C.

  8/1/23 → 7/31/24

  Project: A - Government Institution › b - National Science and Technology Council

• 開發神經內分泌分化前列腺癌之次世代免疫治療(1/3)

  Liu, Y.

  8/1/23 → 7/31/24

  Project: A - Government Institution › b - National Science and Technology Council

• 研究介白素-1受體拮抗劑(IL1RN)在胰臟癌的功能(3/3)

  Tsai, Y.

  8/1/23 → 7/31/24

  Project: A - Government Institution › b - National Science and Technology Council

• 探討TEAD4調控粒線體活性及引發攝護腺癌症的機制(3/5)

  Kung, H.

  8/1/23 → 7/31/24

  Project: A - Government Institution › b - National Science and Technology Council

• 設計與優化新穎蛋白質激酶抑制劑應用於胰臟癌之療效與機轉探討(2/3)

  Hsu, K.

  8/1/23 → 7/31/24

  Project: A - Government Institution › b - National Science and Technology Council

• 透過調整腫瘤細胞中的類固醇合成至别孕烷醇酮和重新編程脂肪酸代謝來促進自然殺手細胞治療膠質母細胞瘤

  Hsu, T.

  8/1/23 → 7/31/24

  Project: A - Government Institution › b - National Science and Technology Council

• 研發新穎性標的 RNA splicing 抑制劑用於治療消化道癌症之智慧型藥物設計與轉譯研究－探討 DYRK1/CLK 抑制劑於人類消化道癌進行 mRNA splicing 調控機制和治療潛力(1/3)

  Pan, S.

  8/1/23 → 7/31/24

  Project: A - Government Institution › b - National Science and Technology Council

• 利用結構生物學與蛋白質體學探討植物菌質體 PHYL1 交互作用蛋白質-第二期研究(3/3)

  Wang, H.

  8/1/23 → 7/31/24

  Project: A - Government Institution › b - National Science and Technology Council

• 脂質薑黃素顆粒(SLCP)在體內對mTOR訊息路徑的作用–尋求以疾病機制為基礎對結節性硬化症(TSC)癲癇的治療策略(3/3)

  Lee, Y.

  8/1/23 → 7/31/24

  Project: A - Government Institution › b - National Science and Technology Council

• 探討引導受體與配體之間的cis-弱化互動對脊髓運動神經迴路形成的影響(3/3)

  Kao, T.

  8/1/23 → 7/31/24

  Project: A - Government Institution › b - National Science and Technology Council

• Investigating potential therapeutic targets of amino acid metabolism in temozolomide -resistance and relapse glioblastoma patients

  Wang, C.

  8/1/23 → 7/31/24

  Project: A - Government Institution › b - National Science and Technology Council

• 探討運動神經元SARM1在漸凍人症的神經軸突退化過程中對許旺細胞與肌肉的影響與機轉(1/2)

  Lin, Y.

  8/1/23 → 7/31/24

  Project: A - Government Institution › b - National Science and Technology Council

• 抗核酸抗體結構特徵研究應用於系統性紅斑狼瘡檢測

  Lee, C.

  8/1/23 → 7/31/24

  Project: A - Government Institution › b - National Science and Technology Council

• 以人工智慧判別糖尿病足傷口影像評估其伴隨周邊血管疾病的風險

  Chiu, H.

  8/1/23 → 7/31/24

  Project: A - Government Institution › b - National Science and Technology Council

• 透過非監督式微生物群基因體分類工具深度挖掘與分析微生物如何影響疾病的產生(3/3)

  Wu, Y.

  8/1/23 → 7/31/24

  Project: A - Government Institution › b - National Science and Technology Council

• 新穎性DYRK1B抑制劑用於胰臟癌之藥理機轉探討與藥物研發(2/3)

  HuangFu, W.

  8/1/23 → 7/31/24

  Project: A - Government Institution › b - National Science and Technology Council

• 探討罕見、不確定重要性與常見致病之基因變異對於前列腺癌風險與發病年齡之影響(2/3)

  Shao, Y.

  8/1/23 → 7/31/24

  Project: A - Government Institution › b - National Science and Technology Council

• 結合新奈米附載劑型與間質幹細胞治療系統應用於糖尿病危重肢體缺血 －利用多功能胜肽之特殊培養方法開發增強型間葉幹細胞和其外秘小體做為治療糖尿病危重肢體缺血之轉譯研究(2/3)

  Wu, A. T.

  8/1/23 → 7/31/24

  Project: A - Government Institution › b - National Science and Technology Council

• 一個重要RNA結合蛋白標的TDP-43的神經功能及它在神經退化疾病上的角色(2/3)

  Shen, C.

  8/1/23 → 7/31/24

  Project: A - Government Institution › b - National Science and Technology Council

• 裝載GM-CSF及標靶奈米粒子疫苗之水膠複合系統用於原位募集並活化樹突細胞以增強腫瘤特異性免疫反應達到抑制癌症轉移之功效(3/3)

  Pan, W.

  8/1/23 → 7/31/24

  Project: A - Government Institution › b - National Science and Technology Council

• 靶向MIR31HG/LncHIFCAR 相關分子網絡在胰腺癌轉移和腫瘤微環境的研究－應用dasatinib老藥新用治療胰腺癌之研究: 探討MIR31HG與上皮間質轉化之角色(1/3)

  Yang, P.

  8/1/23 → 7/31/24

  Project: A - Government Institution › b - National Science and Technology Council

• 利用多維度機器學習來預測腦傷患者的預後

  Lin, M.

  8/1/23 → 7/31/24

  Project: A - Government Institution › b - National Science and Technology Council

• 探討長鏈非編碼核醣核酸Smyca促進同源重組及免疫抑制的機轉以作為三陰性乳癌的潛力治療標的

  Chen, H.

  8/1/23 → 7/31/24

  Project: A - Government Institution › b - National Science and Technology Council