The Anticancer Mechanism of the Ribonucleotide Reductase Inhibiting Drug COH29 Involves Suppression of DNA Repair

Bingsen Zhou (Contributor)
Keqiang Zhang (Contributor)
F. Un (Contributor)
Shuya Hu (Contributor)
Jun Wu (Contributor)
Yan Wang (Contributor)
Xiyong Liu (Contributor)
Hongzhi Li (Contributor)
Zheng Liu (Contributor)
Leila Su (Contributor)
Yun Yen (Contributor)

Dataset

Description

Mechanism of Action Study for COH29 Compare COH29 treatment in DNA-repair deficient cell line with truncated BRCA1 (HCC1937) versus phenotypically normal cell line with exogenous WT BRCA1 expression (HCC1937+BRCA1)

Date made available	2015
Publisher	ArrayExpress

Access Dataset

https://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-55004

1 Article

The novel ribonucleotide reductase inhibitor COH29 inhibits DNA repair in vitros
Chen, M. C., Zhou, B., Zhang, K., Yuan, Y. C., Un, F., Hu, S., Chou, C. M., Chen, C. H., Wu, J., Wang, Y., Liu, X., Smith, D. L., Li, H., Liu, Z., Warden, C. D., Su, L., Malkas, L. H., Chung, Y. M., Hu, M. C. T. & Yen, Y., Jun 1 2015, In: Molecular Pharmacology. 87, 6, p. 996-1005 10 p.
Research output: Contribution to journal › Article › peer-review

Open Access
22 Citations (Scopus)

Cite this

Zhou, B. (Contributor), Zhang, K. (Contributor), Un, F. (Contributor), Hu, S. (Contributor), Wu, J. (Contributor), Wang, Y. (Contributor), Liu, X. (Contributor), Li, H. (Contributor), Liu, Z. (Contributor), Su, L. (Contributor), Yen, Y. (Contributor) (2015). The Anticancer Mechanism of the Ribonucleotide Reductase Inhibiting Drug COH29 Involves Suppression of DNA Repair. ArrayExpress.

The Anticancer Mechanism of the Ribonucleotide Reductase Inhibiting Drug COH29 Involves Suppression of DNA Repair

Description

Access Dataset

Research output

The novel ribonucleotide reductase inhibitor COH29 inhibits DNA repair in vitros

Cite this