Data for: Evaluating the feasibility of applying Cobalt-Hydroxyapatite ingots to radiotherapy markers

  • Wei-Chun Lin (Contributor)
  • Cheng Ming Tang (Contributor)
  • Cheng Chang Lu (Contributor)
  • C. C. Chuang (Creator)



Substitution of cobalt for calcium in hydroxyapatite resulted in CoHA with a higher effective atomic number. This study evaluated various medical imaging characteristics of round CoHA ingots in porcine phantom to demonstrate the feasibility of using CoHA ingots as a radiotherapy marker. CoHA was compressed into round ingots and then implanted into phantom of porcine liver and gelatin phantom of porcine vertebra along with three commercially available radiotherapy markers. The phantom were scanned and photographed using a routine x-ray imager, magnetic resonance imager, computed tomography (CT) imager, and ultrasound imager, respectively, followed by image analysis in ImageJ software. CoHA ingots could be clearly identified with general imaging instruments (X-ray, CT, and ultrasound) and the image size did not change. There were some metal artifacts in the magnetic resonance images. CoHA ingots can be used with most medical imaging instruments to help quickly identify the location and extent of soft-tissue tumors, and are biodegradable, that is, they can be self-absorbed by the body over time to avoid interference with follow-up disease screening
Date made available2020
PublisherMendeley Data

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