Additional file 3: of Combination treatment strategy for pancreatic cancer involving the novel HDAC inhibitor MPT0E028 with a MEK inhibitor beyond K-Ras status

  • Min Wu Chao (Contributor)
  • Li Hsun Chang (Contributor)
  • Huang Ju Tu (Contributor)
  • Chao-Di Chang (Contributor)
  • Mei-Jung Lai (Contributor)
  • Ying Yi Chen (Creator)
  • Jing-Ping Liou (Creator)
  • Che Ming Teng (Contributor)
  • Shiow-Lin Pan (Contributor)



Figure S3. ERK inhibition can downregulate EGFR expression. (A) AsPC-1 cells were treated with indicated concentrations of PD98059 for 24, 48, and 72â h. p-ERK and EGFR protein levels were determined. (B) AsPC-1 cells were transfected with scramble or ERK siRNA for 48â h to evaluate the protein expression of ERK and EGFR. Actin was loaded as an internal control. (TIF 440 kb)
Date made available2019

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