Additional file 1 of A universal in silico V(D)J recombination strategy for developing humanized monoclonal antibodies

Additional file 1. Supplementary information: Table S1. Calculated wRMSDi values of the anti-EGFR a4.6.1 mAb and experimental results. Figure S1. Correlation of wRMSDi with the log(EC50) of the anti-EGFR a4.6.1 mAb. Table S2. Calculated wRMSDi values of the anti-GPC3 YP9.1 scFv and experimental results. Figure S2. Correlation of wRMSDi with the log(EC50) of the anti-GPC3 YP9.1 scFv. Table S3. Calculated wRMSDi values and experimental results of the humanized anti-α4β1 integrin variants. Figure S3. Correlation of wRMSDi with the log(EC50) of humanized anti-α4β1 integrin variants. Table S4. Correlation between RMSDi and log(EC50) or log(KD) with and without weighting adjustments.