Additional file 1: Figure S1. of Thrombospondin-2 promotes prostate cancer bone metastasis by the up-regulation of matrix metalloproteinase-2 through down-regulating miR-376c expression

  • Cheng-Ying Chu (Creator)
  • Po Chun Chen (Contributor)
  • Liang Wei Lin (Creator)
  • Yuan Li Huang (Creator)
  • Tien Huang Lin (Creator)
  • Chun Hao Tsai (Creator)
  • Chih Hsin Tang (Contributor)



TSP-2 induces MMP-2 and inhibits miR-376c expressionsin LNCaP cells. Figure S2. The siRNAs abolished the target genes in PC-3 cells. Figure S3. TSP-2 promotes cell migratory and invasive abilities in PC-3 and DU145 cells. Figure S4. The cell migration, invasion and miR-376c expression were not regulated by chemical inhibitor stimulation in PC-3 and DU145 cells. (PDF 1140 kb)
Date made available2017

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